Product Description |
Recombinant Human TIM-1/HAVCR1 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ser21-Gly295. |
Product Background |
Kidney injury molecule 1 (KIM-1, also known as TIM-1) is markedly upregulated in the proximal tubule after injury and is maladaptive when chronically expressed. KIM-1-mediated epithelial cell phagocytosis of apoptotic cells protects the kidney after acute injury by downregulating innate immunity and inflammation. |
Product Category |
Recombinant Protein / Antibody discovery / Antibody discovery | Others |
Protein |
TIM-1/HAVCR1 |
Synonyms |
HAVcr-1; KIM-1; KIM1; TIMD-1; TIMD1;TIM; TIM-1; TIM1; CD365; HAVCR1; HAVCR; HAVCR-1 |
Accession |
|
Species |
Human |
Biotinylated |
no |
Amino Acid Range |
Ser21-Gly295 |
Molecular Weight |
The protein has a predicted MW of 30.58 kDa. Due to glycosylation, the protein migrates to 95-115 kDa based on Bis-Tris PAGE result. |
Product Tag |
C-His |
Expression System |
HEK293 |
Purity |
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
Endotoxin |
Less than 1 EU per ug by the LAL method. |
Form |
Lyophilized |
Shipping |
Shipped at ambient temperature. |
Formulation |
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution |
Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking. |
Stability And Storage |
-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
|
|
Human TIM-1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. |
|
|
The purity of Human TIM-1 is greater than 95% as determined by SEC-HPLC. |
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