Name: Human TRAIL R1/DR4/TNFRSF10A Protein (TRL-HM2R1)
Brand: KactusBio
SKU: TRL-HM2R1-100UG
Price: 239.8 USD
Availability: InStock

Human TRAIL R1/DR4/TNFRSF10A Protein (TRL-HM2R1)

Immobilized Human TRAIL, No Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Human TRAIL R1, hFc Tag with the EC50 of 11.1ng/ml determined by ELISA.

Human TRAIL R1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

The purity of Human TRAIL R1 is greater than 95% as determined by SEC-HPLC.

Express System: HEK293
Product Tag: C-hFc
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: Immobilized Human TRAIL, No Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Human TRAIL R1, hFc Tag with the EC50 of 11.1ng/ml determined by ELISA. See testing image for detail.
Amino Acid Range: Pro34-Asn239

Catalog #TRL-HM2R1

Size

100UG

500UG

Order now, ships by:

[{"id":42618400243934,"title":"100UG","option1":"100UG","option2":null,"option3":null,"sku":"TRL-HM2R1-100UG","requires_shipping":true,"taxable":true,"featured_image":null,"available":true,"name":"Human TRAIL R1\/DR4\/TNFRSF10A Protein (TRL-HM2R1) - 100UG","public_title":"100UG","options":["100UG"],"price":23980,"weight":5,"compare_at_price":null,"inventory_management":"shopify","barcode":null,"requires_selling_plan":false,"selling_plan_allocations":[],"quantity_rule":{"min":1,"max":null,"increment":1}},{"id":43584169935070,"title":"500UG","option1":"500UG","option2":null,"option3":null,"sku":"TRL-HM2R1-500UG","requires_shipping":true,"taxable":true,"featured_image":null,"available":true,"name":"Human TRAIL R1\/DR4\/TNFRSF10A Protein (TRL-HM2R1) - 500UG","public_title":"500UG","options":["500UG"],"price":79750,"weight":5,"compare_at_price":null,"inventory_management":"shopify","barcode":null,"requires_selling_plan":false,"selling_plan_allocations":[],"quantity_rule":{"min":1,"max":null,"increment":1}}]

Product Description	Recombinant Human TRAIL R1/DR4/TNFRSF10A Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Pro34-Asn239.
Product Background	Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) induces apoptosis selectively via its interaction with the death receptors TRAILR1/DR4 and TRAILR2/DR5 in a wide range of cancers, while sparing normal cells. Despite its tremendous potential for cancer therapeutics, the translation of TRAIL into the clinic has been confounded by TRAIL-resistant cancer populations.
Product Category	Recombinant Protein / Antibody discovery

Protein	TRAIL R1/DR4/TNFRSF10A
Synonyms	DR4; CD261; TNFRSF10A; TRAIL-R; APO2; TRAIL R1; MGC9365
Accession	O00220
Species	Human
Biotinylated	no
Amino Acid Range	Pro34-Asn239
Molecular Weight	The protein has a predicted MW of 48.8 kDa. Due to glycosylation, the protein migrates to 50-60 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Human TRAIL, No Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Human TRAIL R1, hFc Tag with the EC50 of 11.1ng/ml determined by ELISA. See testing image for detail.
Product Tag	C-hFc
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Human TRAIL, No Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Human TRAIL R1, hFc Tag with the EC50 of 11.1ng/ml determined by ELISA.
	Human TRAIL R1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Human TRAIL R1 is greater than 95% as determined by SEC-HPLC.