Name: Mouse IFN alpha/beta R1 Protein (IFN-MM2R1)
Brand: KactusBio
SKU: IFN-MM2R1-100UG
Price: 330.0 USD
Availability: InStock

Mouse IFN alpha/beta R1 Protein (IFN-MM2R1)

Mouse IFN alpha/beta R1, hFc Tag immobilized on CM5 Chip can bind Human IFN alpha 1, hFc Tag with an affinity constant of 20.35 nM as determined in SPR assay (Biacore T200).

Mouse IFNAR1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

Express System: HEK293
Product Tag: C-hFc
Purity: > 95% as determined by Bis-Tris PAGE
Activity: The affinity constant of 20.35 nM as determined in SPR assay (Biacore T200). See testing image for detail.
Amino Acid Range: Glu27-Thr429

Catalog #IFN-MM2R1

Size

100UG

500UG

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Product Description	Recombinant Mouse IFN alpha/beta R1 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Glu27-Thr429.
Product Background	IFN-alpha / beta R1, also known as IFNAR1, belongs to the class II cytokine receptor family of proteins. Class II cytokine receptors form heterodimeric receptor complexes that mediate class II cytokine signals. Subunits of the different receptor complexes are shared and serve multiple functions.Functions in general as heterodimer with IFNAR2. Type I interferon binding activates the JAK-STAT signaling cascade, and triggers tyrosine phosphorylation of a number of proteins including JAKs, TYK2, STAT proteins and the IFNR alpha- and beta-subunits themselves.
Product Category	Recombinant Protein / Antibody discovery

Protein	IFN alpha/beta R1
Synonyms	AVP; IFN-alpha/beta R1; IFN-alpha-REC; IFNAR; IFNAR1; IFN-aR1; IFNBR; IFNbR1; IFN-R-1; CRF2-1; IFRC ; IFN-alpha/β R1
Accession	P33896
Species	Mouse
Biotinylated	no
Amino Acid Range	Glu27-Thr429
Molecular Weight	The protein has a predicted MW of 72.5 kDa. Due to glycosylation, the protein migrates to 83-110 kDa based on Bis-Tris PAGE result.
Activity	The affinity constant of 20.35 nM as determined in SPR assay (Biacore T200). See testing image for detail.
Product Tag	C-hFc
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Mouse IFN alpha/beta R1, hFc Tag immobilized on CM5 Chip can bind Human IFN alpha 1, hFc Tag with an affinity constant of 20.35 nM as determined in SPR assay (Biacore T200).
	Mouse IFNAR1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.