Mouse IL-3 R alpha/CD123 Protein (IL3-MM1RA)
Mouse IL-3 R alpha/CD123 Protein (IL3-MM1RA)
  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Amino Acid Range: Ser17-Lys331
Catalog #IL3-MM1RA
Regular price $346.50
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Product Description

Recombinant Mouse IL-3 R alpha/CD123 Protein is expressed from HEK293 with His tag at the C-terminus.It contains Ser17-Lys331.

Product Background

Interleukin-3 receptor subunit alpha, also known as IL-3 receptor subunit alpha, IL-3R-alpha, CD123, and IL3RA, is a single-pass type I membrane protein which belongs to the type I cytokine receptor family and Type 5 subfamily.The specific alpha subunit of the interleukin-3 receptor (IL-3Ralpha, CD123) is strongly expressed in various leukemic blasts and leukemic stem cells and seems to be an excellent target for the therapy of leukemias.

Product Category

Recombinant Protein / Antibody discovery / CAR-T targets
Protein
IL-3 R alpha/CD123
Synonyms
CD123; IL-3R subunit alpha; IL3R; IL3RA; IL-3Ra; IL3RAY; IL3RX; IL3RY; IL-3 R alpha
Accession
Species
Mouse
Biotinylated
no
Amino Acid Range
Ser17-Lys331
Molecular Weight
The protein has a predicted MW of 36.12 kDa. Due to glycosylation, the protein migrates to 55-70 kDa based on Bis-Tris PAGE result.

Product Tag

C-His
Expression System
HEK293
Purity
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin
Less than 1 EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage
-20 to -80°C for 12 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Mouse IL-3 R alpha on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Mouse IL-3 R alpha on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Mouse IL-3 R alpha is greater than 95% as determined by SEC-HPLC. The purity of Mouse IL-3 R alpha is greater than 95% as determined by SEC-HPLC.
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