Name: Mouse Integrin alpha 2 beta 1 (ITGA2&ITGB1) Heterodimer Protein (ITG-MM1AB)
Brand: KactusBio
SKU: ITG-MM1AB-100UG
Price: 412.5 USD
Availability: InStock

Mouse Integrin alpha 2 beta 1 (ITGA2&ITGB1) Heterodimer Protein (ITG-MM1AB)

Mouse ITGA2&ITGB1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

The purity of Mouse ITGA2&ITGB1 is greater than 95% as determined by SEC-HPLC.

Express System: HEK293
Product Tag: C-His
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Amino Acid Range: Tyr27-Thr1129(ITGA2) acidic tail & Gln21-Asp728(ITGB1) basic tail

Catalog #ITG-MM1AB

Size

100UG

500UG

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Product Description	Recombinant Mouse Integrin alpha 2 beta 1(ITGA2&ITGB1) Heterodimer Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Tyr27-Thr1129(ITGA2) acidic tail & Gln21-Asp728(ITGB1) basic tail.
Product Background	Integrin alpha 2 beta 1 is a positive regulator of collagenase (MMP-1) and collagen alpha 1(I) gene expression.HOS cells normally lacking alpha 2 beta 1 integrin were forced to express it, and this prevented the down-regulation in the levels of alpha 1 (I) collagen mRNA when cells were grown inside collagen gels. The data indicate that the level of MMP-1 expression is regulated by the collagen receptor alpha 2 beta 1 integrin.
Product Category	Recombinant Protein / Antibody discovery

Protein	Integrin alpha 2 beta 1 (ITGA2&ITGB1) Heterodimer
Synonyms	α2β1; ITGA2&ITGB1; ITGA2; ITGB1;
Accession	Q62469(ITGA2)&P09055-1(ITGB1)
Species	Mouse
Biotinylated	no
Amino Acid Range	Tyr27-Thr1129(ITGA2) acidic tail & Gln21-Asp728(ITGB1) basic tail
Molecular Weight	The protein has a predicted MW of 126.60 kDa(ITGA2)&82.80 kDa(ITGB1). Due to glycosylation, the protein migrates to 128-138 kDa(ITGA2)&105-115 kDa(ITGB1) based on Bis-Tris PAGE result.
Product Tag	C-His
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Mouse ITGA2&ITGB1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Mouse ITGA2&ITGB1 is greater than 95% as determined by SEC-HPLC.