Name: Mouse Integrin alpha 2 beta 1 (ITGA2&ITGB1) Heterodimer Protein (ITG-MM1AB)
Brand: KactusBio
SKU: ITG-MM1AB-100UG
Price: 412.5 USD
Availability: InStock

SEC-HPLC chromatogram of recombinant protein with a sharp main peak at 7.0 minutes, indicating high monomer purity.

Mouse Integrin alpha 2 beta 1 (ITGA2&ITGB1) Heterodimer Protein (ITG-MM1AB)

Mouse ITGA2&ITGB1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

The purity of Mouse ITGA2&ITGB1 is greater than 95% as determined by SEC-HPLC.

Express System: HEK293
Product Tag: C-His
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Amino Acid Range: Tyr27-Thr1129(ITGA2) acidic tail & Gln21-Asp728(ITGB1) basic tail

Catalog #ITG-MM1AB

Size

100UG

500UG

Order now, ships by:

[{"id":42618370883806,"title":"100UG","option1":"100UG","option2":null,"option3":null,"sku":"ITG-MM1AB-100UG","requires_shipping":true,"taxable":true,"featured_image":null,"available":true,"name":"Mouse Integrin alpha 2 beta 1 (ITGA2\u0026ITGB1) Heterodimer Protein (ITG-MM1AB) - 100UG","public_title":"100UG","options":["100UG"],"price":41250,"weight":5,"compare_at_price":null,"inventory_management":"shopify","barcode":null,"requires_selling_plan":false,"selling_plan_allocations":[],"quantity_rule":{"min":1,"max":null,"increment":1}},{"id":43584159973598,"title":"500UG","option1":"500UG","option2":null,"option3":null,"sku":"ITG-MM1AB-500UG","requires_shipping":true,"taxable":true,"featured_image":null,"available":true,"name":"Mouse Integrin alpha 2 beta 1 (ITGA2\u0026ITGB1) Heterodimer Protein (ITG-MM1AB) - 500UG","public_title":"500UG","options":["500UG"],"price":137500,"weight":5,"compare_at_price":null,"inventory_management":"shopify","barcode":null,"requires_selling_plan":false,"selling_plan_allocations":[],"quantity_rule":{"min":1,"max":null,"increment":1}}]

Product Description	Recombinant Mouse Integrin alpha 2 beta 1(ITGA2&ITGB1) Heterodimer Protein is expressed from HEK293 with His tag at the C-Terminus of ITGA2.It contains Tyr27-Thr1129(ITGA2) acidic tail and Gln21-Asp728(ITGB1) basic tail.
Product Background	Integrin alpha 2 beta 1 is a positive regulator of collagenase (MMP-1) and collagen alpha 1(I) gene expression.HOS cells normally lacking alpha 2 beta 1 integrin were forced to express it, and this prevented the down-regulation in the levels of alpha 1 (I) collagen mRNA when cells were grown inside collagen gels. The data indicate that the level of MMP-1 expression is regulated by the collagen receptor alpha 2 beta 1 integrin.
Product Category	Recombinant Protein / Antibody discovery / Antibody discovery \| Others

Protein	Integrin alpha 2 beta 1 (ITGA2&ITGB1) Heterodimer
Synonyms	α2β1; ITGA2&ITGB1; ITGA2; ITGB1;
Accession	Q62469(ITGA2)&P09055-1(ITGB1)
Species	Mouse
Biotinylated	no
Amino Acid Range	Tyr27-Thr1129(ITGA2) acidic tail & Gln21-Asp728(ITGB1) basic tail
Molecular Weight	The protein has a predicted MW of 126.60 kDa(ITGA2)&82.80 kDa(ITGB1). Due to glycosylation, the protein migrates to 128-138 kDa(ITGA2)&105-115 kDa(ITGB1) based on Bis-Tris PAGE result.
Product Tag	C-His
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1 EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Mouse ITGA2&ITGB1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Mouse ITGA2&ITGB1 is greater than 95% as determined by SEC-HPLC.