Mouse Integrin alpha V beta 3 (ITGAV&ITGB3) Heterodimer Protein (ITG-MM2V3)

  • Express System: Expi293
  • Product Tag: C-hFc
  • Purity: > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
  • Activity: The affinity constant of 3.37 nM as determined in SPR assay (Biacore T200). See testing image for detail.
  • Exact Sequence: Phe31-Val988(ITGAV)acidic tail & Glu26-Asp717(ITGB3)basic tail

Catalog: ITG-MM2V3

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Product Description Recombinant Mouse Integrin alpha V beta 3 (ITGAV&ITGB3) Heterodimer Protein is expressed from Expi293 with hFc tag at the C-terminal.It contains Phe31-Val988(ITGAV) acidic tail & Glu26-Asp717(ITGB3) basic tail.
Product Category Recombinant Protein
Target Integrin alpha V beta 3 (ITGAV&ITGB3) Heterodimer
Gene/Protein ID P43406(ITGAV)&&O54890(ITGB3)
Species Mouse
Exact Sequence Phe31-Val988(ITGAV)acidic tail & Glu26-Asp717(ITGB3)basic tail
Molecular Weight The protein has a predicted MW of 131.48 kDa(ITGAV)&101.58 kDa(ITGB3). Due to enzyme lysis and glycosylation, the protein migrates to 110-135 kDa and 50-60 kDa based on Tris-Bis PAGE result.
Activity The affinity constant of 3.37 nM as determined in SPR assay (Biacore T200). See testing image for detail.
Product Tag C-hFc
Express System Expi293
Purity > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin Less than 1EU per μg by the LAL method.
Form Lyophilized
Shipping Shipped at ambient temperature.
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution Centrifuge tubes before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Mouse ITGAV&ITGB3, hFc Tag captured on CM5 Chip via Protein A can bind Human Vitronectin, His Tag with an affinity constant of 3.37 nM as determined in SPR assay (Biacore T200).
The purity of Mouse ITGAV&ITGB3 is greater than 95% as determined by SEC-HPLC.
Mouse ITGAV&ITGB3 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

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