Mouse PILRA Protein (PRA-MM201)
Mouse PILRA Protein (PRA-MM201)
  • Express System: HEK293
  • Product Tag: C-hFc
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Amino Acid Range: Glu32-Val197
Catalog #PRA-MM201
Regular price $270.00
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Product Description
Recombinant Mouse PILRA Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Glu32-Val197.
Product Background
Alzheimer's disease (AD) is a neurodegenerative disease characterized by a progressive decline in cognitive performance; Mild Cognitive Impairment (MCI) is instead an objective decline in cognitive performance that does not reach pathology. Paired immunoglobulin-like type 2 receptor alpha (PILRA) is a cell surface inhibitory receptor that was recently suggested to be involved in AD pathogenesis. In particular, the arginine-to-glycine substitution in position 78 (R78, rs1859788) was shown to be protective against AD.
Product Category
Recombinant Protein
Target
PILRA
Synonyms
PILRA; FDF03; PILRalpha; PILR-alpha
Accession
Species
Mouse
Biotinylated
no
Amino Acid Range
Glu32-Val197
Molecular Weight
The protein has a predicted MW of 45.4 kDa. Due to glycosylation, the protein migrates to 70-75 kDa based on Bis-Tris PAGE result.
Product Tag
C-hFc
Express System
HEK293
Purity
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin
Less than 1EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage
Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Mouse PILRA on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Mouse PILRA is greater than 95% as determined by SEC-HPLC.

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