Mouse TRAIL/TNFRSF10 Protein (TRL-ME101)
Mouse TRAIL/TNFRSF10 Protein (TRL-ME101)
  • Express System: E.coli
  • Product Tag: N-His
  • Purity: > 95% as determined by Bis-Tris PAGE
  • Activity: The affinity constant of 0.62 uM as determined in SPR assay (Biacore T200). See testing image for detail.
  • Amino Acid Range: Pro118-Asn291
Catalog #TRL-ME101
Regular price $218.00
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Product Description
Recombinant Mouse TRAIL/TNFRSF10 Protein is expressed from E.coli with His tag at the N-Terminus.It contains Pro118-Asn291.
Product Background
Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) is a member of the TNF superfamily that can initiate the apoptosis pathway by binding to its associated death receptors DR4 and DR5. The activation of the TRAIL pathway in inducing tumor-selective apoptosis leads to the development of TRAIL-based cancer therapies, which include recombinant forms of TRAIL, TRAIL receptor agonists, and other therapeutic agents.
Product Category
Recombinant Protein
Target
TRAIL/TNFRSF10
Synonyms
Apo-2L; TRAIL; CD253; TNFSF10; Apo-2 ligand; APO2L; TL2
Accession
Species
Mouse
Biotinylated
no
Amino Acid Range
Pro118-Asn291
Molecular Weight
The protein has a predicted MW of 30.6 kDa same as Bis-Tris PAGE result.
Activity
The affinity constant of 0.62 uM as determined in SPR assay (Biacore T200). See testing image for detail.
Product Tag
N-His
Express System
E.coli
Purity
> 95% as determined by Bis-Tris PAGE
Endotoxin
Less than 1EU per ug by the LAL method.
Form
Liquid
Shipping
Shipped with dry ice.
Formulation
Supplied as 0.22um filtered solution in 0.1M Glycine, 150mM NaCl, 10% Glycerol (pH 3.0).
Stability And Storage
Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Human TRAIL R1, hFc Tag captured on CM5 Chip via Protein A can bind Mouse TRAIL, His Tag with an affinity constant of 0.62 uM as determined in SPR assay (Biacore T200).
Mouse TRAIL on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

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