Product Description |
Recombinant Mouse TRAIL/TNFRSF10 Protein is expressed from E.coli with His tag at the N-Terminus.It contains Pro118-Asn291. |
Product Background |
Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) is a member of the TNF superfamily that can initiate the apoptosis pathway by binding to its associated death receptors DR4 and DR5. The activation of the TRAIL pathway in inducing tumor-selective apoptosis leads to the development of TRAIL-based cancer therapies, which include recombinant forms of TRAIL, TRAIL receptor agonists, and other therapeutic agents. |
Product Category |
Recombinant Protein |
Target |
TRAIL/TNFRSF10 |
Synonyms |
Apo-2L; TRAIL; CD253; TNFSF10; Apo-2 ligand; APO2L; TL2 |
Accession |
|
Species |
Mouse |
Biotinylated |
no |
Amino Acid Range |
Pro118-Asn291 |
Molecular Weight |
The protein has a predicted MW of 30.6 kDa same as Bis-Tris PAGE result. |
Activity |
The affinity constant of 0.62 uM as determined in SPR assay (Biacore T200). See testing image for detail. |
Product Tag |
N-His |
Express System |
E.coli |
Purity |
> 95% as determined by Bis-Tris PAGE |
Endotoxin |
Less than 1EU per ug by the LAL method. |
Form |
Liquid |
Shipping |
Shipped with dry ice. |
Formulation |
Supplied as 0.22um filtered solution in 0.1M Glycine, 150mM NaCl, 10% Glycerol (pH 3.0). |
Stability And Storage |
Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
|
|
Human TRAIL R1, hFc Tag captured on CM5 Chip via Protein A can bind Mouse TRAIL, His Tag with an affinity constant of 0.62 uM as determined in SPR assay (Biacore T200). |
|
|
Mouse TRAIL on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. |
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