HPLC chromatogram of purified protein sample with a dominant peak at 7.321 minutes, indicating high sample homogeneity.
Canine Oncostatin M/OSM-Protein (OSM-DM10M)
  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Amino Acid Range: Ser27-Arg207
Catalog #OSM-DM10M
Regular price $346.50
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Product Description

Recombinant Canine Oncostatin M/OSM-Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ser27-Arg207.

Product Background

OSM is a pleiotropic cytokine that initiates its biological activities by binding to specific cell surface receptors. Inhibits the proliferation of a number of tumor cell lines. Stimulates proliferation of AIDS-KS cells. It regulates cytokine production, including IL-6, G-CSF and GM-CSF from endothelial cells. Uses both type I OSM receptor (heterodimers composed of LIFR and IL6ST) and type II OSM receptor (heterodimers composed of OSMR and IL6ST). Involved in the maturation of fetal hepatocytes, thereby promoting liver development and regeneration.

Product Category

Recombinant Protein / Antibody discovery / Antibody discovery | Others
Protein
Oncostatin M/OSM
Synonyms
Oncostatin M; OSM; MGC20461
Accession
Species
Canine
Biotinylated
no
Amino Acid Range
Ser27-Arg207
Molecular Weight
The protein has a predicted MW of 21.65 kDa. Due to glycosylation, the protein migrates to 27-35 kDa based on Bis-Tris PAGE result.

Product Tag

C-His
Expression System
HEK293
Purity
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin
Less than 1 EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage
-20 to -80°C for 12 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Canine Oncostatin M on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Canine Oncostatin M on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Canine Oncostatin M is greater than 95% as determined by SEC-HPLC. The purity of Canine Oncostatin M is greater than 95% as determined by SEC-HPLC.
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