Name: Cynomolgus AXL Protein (AXL-CM102)
Brand: KactusBio
SKU: AXL-CM102-100UG
Price: 270.0 USD
Availability: InStock

Express System: HEK293
Product Tag: C-His
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: Immobilized Cynomolgus AXL, His Tag at 0.5ug/ml (100ul/Well) on the plate. Dose response curve for Anti-AXL Antibody, hFc Tag with the EC50 of 8.8ng/ml determined by ELISA (QC Test). The affinity constant of 1.70 nM as determined in SPR assay (Biacore T200). See testing image for detail.
Amino Acid Range: Glu33-Pro449

Catalog #AXL-CM102

Size

100UG

500UG

Order now, ships by:

Product Description	Recombinant Cynomolgus AXL Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Glu33-Pro449.
Product Background	Axl, a member of the TAM (Tyro3, Axl, Mer) family, and its inhibitors can specifically break the kinase signaling nodes, allowing advanced patients to regain drug sensitivity with improved therapeutic efficacy. Overexpression and activation of Axl receptor tyrosine kinase have been widely accepted to promote cell proliferation, chemotherapy resistance, invasion, and metastasis in several human cancers, such as lung, breast, and pancreatic cancers.
Product Category	Recombinant Protein / Antibody discovery

Protein	AXL
Synonyms	Axl; UFO; AXL oncogene; AXL; ARK; JTK11; Tyro7; AI323647; EC 2.7.10; EC 2.7.10.1
Accession	A0A1D5Q330
Species	Cynomolgus
Biotinylated	no
Amino Acid Range	Glu33-Pro449
Molecular Weight	The protein has a predicted MW of 46.3 kDa. Due to glycosylation, the protein migrates to 68-70 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Cynomolgus AXL, His Tag at 0.5ug/ml (100ul/Well) on the plate. Dose response curve for Anti-AXL Antibody, hFc Tag with the EC50 of 8.8ng/ml determined by ELISA (QC Test). The affinity constant of 1.70 nM as determined in SPR assay (Biacore T200). See testing image for detail.
Product Tag	C-His
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Cynomolgus Axl, His Tag immobilized on CM5 Chip can bind Cynomolgus GAS6, His Tag with an affinity constant of 1.70 nM as determined in SPR assay (Biacore T200).
	Immobilized Cynomolgus AXL, His Tag at 0.5ug/ml (100ul/Well) on the plate. Dose response curve for Anti-AXL Antibody, hFc Tag with the EC50 of 8.8ng/ml determined by ELISA (QC Test).
	Cynomolgus AXL on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Cynomolgus AXL is greater than 95% as determined by SEC-HPLC.

Check out our Frequently Asked Questions page for more details about product specifications, ordering, and shipments.

Product Description

Product Background