Name: Cynomolgus CRTAM Protein (CRM-CM101)
Brand: KactusBio
SKU: CRM-CM101-100UG
Price: 240.0 USD
Availability: InStock

Express System: HEK293
Product Tag: C-His
Purity: > 95% as determined by Bis-Tris PAGE
Activity: Immobilized Cynomolgus CRTAM, His Tag at 2ug/ml (100ul/Well) on the plate. Dose response curve for Anti-CRTAM Antibody, hFc Tag with the EC50 of 13.0ng/ml determined by ELISA (QC Test) See testing image for detail.
Amino Acid Range: Ser18-Gly287

Catalog #CRM-CM101

Size

100UG

500UG

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Product Description	Recombinant Cynomolgus CRTAM Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ser18-Gly287.
Product Background	Class-I Restricted T Cell-Associated Molecule (CRTAM) is a protein that is expressed after T cell activation. The interaction of CRTAM with its ligand, nectin-like 2 (Necl2), is required for the efficient production of IL-17, IL-22, and IFNγ by murine CD4 T cells, and it plays a role in optimal CD8 T and NK cell cytotoxicity. CRTAM promotes the pro-inflammatory cytokine profile; therefore, it may take part in the immunopathology of autoimmune diseases such as diabetes type 1 or colitis.
Product Category	Recombinant Protein / Antibody discovery

Protein	CRTAM
Synonyms	CD355 antigen; CD355; CRTAM
Accession	XP_005580021.1
Species	Cynomolgus
Biotinylated	no
Amino Acid Range	Ser18-Gly287
Molecular Weight	The protein has a predicted MW of 30.80 kDa. Due to glycosylation, the protein migrates to 50-70 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Cynomolgus CRTAM, His Tag at 2ug/ml (100ul/Well) on the plate. Dose response curve for Anti-CRTAM Antibody, hFc Tag with the EC50 of 13.0ng/ml determined by ELISA (QC Test) See testing image for detail.
Product Tag	C-His
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE
Endotoxin	Less than 0.1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Cynomolgus CRTAM, His Tag at 2ug/ml (100ul/Well) on the plate. Dose response curve for Anti-CRTAM Antibody, hFc Tag with the EC50 of 13.0ng/ml determined by ELISA (QC Test)
	Cynomolgus CRTAM on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.