Cynomolgus FcRH5/FcRL5 Protein (FCR-CM101)
Cynomolgus FcRH5/FcRL5 Protein (FCR-CM101)
  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Bis-Tris PAGE
  • Activity: Immobilized Anti-FcRH5 Antibody, hFc Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Cynomolgus FcRH5, His Tag with the EC50 of 0.54ug/ml determined by ELISA (QC Test). The affinity constant of 0.14 uM as determined in SPR assay (Biacore T200). See testing image for detail.
  • Amino Acid Range: Gln16-Gly851
Catalog #FCR-CM101
Regular price $346.50
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Product Description

Recombinant Cynomolgus FcRH5/FcRL5 Protein is expressed from HEK293 with His tag at the C-terminus.It contains Gln16-Gly851.

Product Background

FcRH5 is a cell surface marker enriched on malignant plasma cells when compared to other hematologic malignancies and normal tissues. DFRF4539A is an anti-FcRH5 antibody-drug conjugated to monomethyl auristatin E (MMAE), a potent anti-mitotic agent.

Product Category

Recombinant Protein / Antibody discovery / Antibody discovery | Others
Protein
FcRH5/FcRL5
Synonyms
FcR-like protein 5; FcRH5; FcRL5; BXMAS1; CD307; CD307e; IFGP5; IRTA2
Accession
Species
Cynomolgus
Biotinylated
no
Amino Acid Range
Gln16-Gly851
Molecular Weight
The protein has a predicted MW of 92.13 kDa. Due to glycosylation, the protein migrates to 100-130 kDa based on Bis-Tris PAGE result.
Activity
Immobilized Anti-FcRH5 Antibody, hFc Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Cynomolgus FcRH5, His Tag with the EC50 of 0.54ug/ml determined by ELISA (QC Test). The affinity constant of 0.14 uM as determined in SPR assay (Biacore T200). See testing image for detail.

Product Tag

C-His
Expression System
HEK293
Purity
> 95% as determined by Bis-Tris PAGE
Endotoxin
Less than 1 EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage
-20 to -80°C for 12 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Cynomolgus FcRH5, His Tag captured on CM5 Chip via Anti-His Antibody can bind Anti-FcRH5 Ab., hFc Tag with an affinity constant of 0.14 uM as determined in SPR assay (Biacore T200). Cynomolgus FcRH5, His Tag captured on CM5 Chip via Anti-His Antibody can bind Anti-FcRH5 Ab., hFc Tag with an affinity constant of 0.14 uM as determined in SPR assay (Biacore T200).
Immobilized Anti-FcRH5 Antibody, hFc Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Cynomolgus FcRH5, His Tag with the EC50 of 0.54ug/ml determined by ELISA (QC Test). Immobilized Anti-FcRH5 Antibody, hFc Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Cynomolgus FcRH5, His Tag with the EC50 of 0.54ug/ml determined by ELISA (QC Test).
Cynomolgus FcRH5 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Cynomolgus FcRH5 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
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