Name: Cynomolgus IL-18 R1/CD218a Protein (IL8-CM1R1)
Brand: KactusBio
SKU: IL8-CM1R1-100UG
Price: 346.5 USD
Availability: InStock

Cynomolgus IL-18 R1/CD218a Protein (IL8-CM1R1)

Cynomolgus IL-18 R1, His Tag captured on CM5 Chip via anti-his antibody can bind Human IL-18, No Tag with an affinity constant of 2.02 nM as determined in SPR assay (Biacore T200).

Cynomolgus IL-18 R1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

The purity of Cynomolgus IL-18 R1 is greater than 95% as determined by SEC-HPLC.

Express System: HEK293
Product Tag: C-His
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: The affinity constant of 2.02 nM as determined in SPR assay (Biacore T200). See testing image for detail.
Amino Acid Range: Cys22-Gly329

Catalog #IL8-CM1R1

Size

100UG

500UG

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Product Description	Recombinant Cynomolgus IL-18 R1/CD218a Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Cys22-Gly329.
Product Background	Interleukin-18 (IL-18) is a member of the interleukin-1 family of cytokines produced constitutively by different cell types and by adipose tissue. Interleukin (IL)-18 was originally discovered as a factor that enhanced IFN-γ production from anti-CD3-stimulated Th1 cells, especially in the presence of IL-12. Upon stimulation with Ag plus IL-12, naïve T cells develop into IL-18 receptor (IL-18R) expressing Th1 cells, which increase IFN-γ production in response to IL-18 stimulation.
Product Category	Recombinant Protein / Antibody discovery / Antibody discovery \| Others

Protein	IL-18 R1/CD218a
Synonyms	CD218a; IL18Ra; IL18R1; IL1RRP; IL-1 R5; IL-1 Rrp; IL-18 R alpha; IL-18 R1; IL-18Ra
Accession	A0A2K5V3J9
Species	Cynomolgus
Biotinylated	no
Amino Acid Range	Cys22-Gly329
Molecular Weight	The protein has a predicted MW of 36.45 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Bis-Tris PAGE result.
Activity	The affinity constant of 2.02 nM as determined in SPR assay (Biacore T200). See testing image for detail.
Product Tag	C-His
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1 EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Cynomolgus IL-18 R1, His Tag captured on CM5 Chip via anti-his antibody can bind Human IL-18, No Tag with an affinity constant of 2.02 nM as determined in SPR assay (Biacore T200).
	Cynomolgus IL-18 R1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Cynomolgus IL-18 R1 is greater than 95% as determined by SEC-HPLC.