Cynomolgus RGM-C Protein (RGM-CM10C)
Cynomolgus RGM-C Protein (RGM-CM10C)
Cynomolgus RGM-C Protein (RGM-CM10C)
Cynomolgus RGM-C Protein (RGM-CM10C)
  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Activity: Immobilized Cynomolgus RGM-C, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-RGM-C Antibody, hFc Tag with the EC50 of 1.7ng/ml determined by ELISA. See testing image for detail.
  • Amino Acid Range: Gln36-Asp401
Catalog #RGM-CM10C
Regular price $346.50
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Product Description

Recombinant Cynomolgus RGM-C Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Gln36-Asp401.

Product Background

RGM gene family ('Repulsive Axonal Guidance molecules' A, B and C),both RGM A and B are mostly expressed in central nervous system, while RGM C is exclusively expressed in all striated muscle and in the myocardium. RGM A and B appear at every level of the developing neural axis, where they colocalize to a large extent in the mantle layer, although only RGM A appears in the neuroepithelium, and only RGM B in the peripheral nervous system.

Product Category

Recombinant Protein / Antibody discovery / Antibody discovery | Others
Protein
RGM-C
Synonyms
Hemojuvelin; Rgmc; DL-M; HFE2; HFE2AMGC23953; HJV; JH; RGMC; RGM-C
Accession
Species
Cynomolgus
Biotinylated
no
Amino Acid Range
Gln36-Asp401
Molecular Weight
The protein has a predicted MW of 40 kDa (mature)&26 kDa (C-terminus peptide)&14 kDa (N-terminus peptide). Due to enzyme lysis and glycosylation, the protein migrates to 50-60 kDa&30-40 kDa&20-25 kDa based on Bis-Tris PAGE result.
Activity
Immobilized Cynomolgus RGM-C, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-RGM-C Antibody, hFc Tag with the EC50 of 1.7ng/ml determined by ELISA. See testing image for detail.

Product Tag

C-His
Expression System
HEK293
Purity
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin
Less than 1 EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage
-20 to -80°C for 12 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Immobilized Cynomolgus RGM-C, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-RGM-C Antibody, hFc Tag with the EC50 of 1.7ng/ml determined by ELISA. Immobilized Cynomolgus RGM-C, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-RGM-C Antibody, hFc Tag with the EC50 of 1.7ng/ml determined by ELISA.
Cynomolgus RGM-C on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Cynomolgus RGM-C on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Cynomolgus RGM-C is greater than 95% as determined by SEC-HPLC. The purity of Cynomolgus RGM-C is greater than 95% as determined by SEC-HPLC.
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