FITC-equivalent Human GPRC5D Protein-VLP (GPR-HM0P11)
  • Express System: HEK293
  • Purity: > 95% as determined by HPLC
  • Activity: Immobilized FITC-equivalent Human GPRC5D VLP at 5ug/ml (100ul/well) on the plate. Dose response curve for Anti-GPRC5D Antibody, hFc Tag with the EC50 of 4.9ng/ml determined by ELISA (QC Test). See testing image for detail.
  • Amino Acid Range: Met1-Val345
Catalog #GPR-HM0P11
Regular price $1,210.00
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Product Description

Recombinant FITC-equivalent Human GPRC5D Protein-VLP is expressed from HEK293.It contains Met1-Val345 (It may have cross reaction with anti-His antibody).

Product Background

Chimeric antigen receptor (CAR) T cells, a type of cell-based immunotherapy, have shown some promising results in multiple myeloma, a bone marrow cancer.The orphan G protein–coupled receptor, class C group 5 member D (GPRC5D), normally expressed only in the hair follicle, Using quantitative immunofluorescence, we determined that GPRC5D protein is expressed on CD138 MM cells from primary marrow samples with a distribution that was similar to, but independent of, BCMA.

Product Category

Recombinant Protein / Antibody discovery / Multiple transmembrane proteins / VLP
Protein
GPRC5D
Synonyms
GPRC5D; MGC129713; MGC129714; orphan G-protein coupled receptor
Accession
Species
Human
Biotinylated
no
Amino Acid Range
Met1-Val345
Molecular Weight
The target protein has a predicted MW of 41.50 kDa.
Activity
Immobilized FITC-equivalent Human GPRC5D VLP at 5ug/ml (100ul/well) on the plate. Dose response curve for Anti-GPRC5D Antibody, hFc Tag with the EC50 of 4.9ng/ml determined by ELISA (QC Test). See testing image for detail.

Fluorophore

FITC
Expression System
HEK293
Purity
> 95% as determined by HPLC
Endotoxin
Less than 1 EU per ug by the LAL method.
Form
Liquid
Shipping
Shipped with dry ice.
Formulation
Supplied as 0.22 um filtered solution in PBS, 150mM L-Arginine (pH 7.4).
Stability And Storage
Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Immobilized FITC-equivalent Human GPRC5D VLP at 5ug/ml (100ul/well) on the plate. Dose response curve for Anti-GPRC5D Antibody, hFc Tag with the EC50 of 4.9ng/ml determined by ELISA (QC Test). Immobilized FITC-equivalent Human GPRC5D VLP at 5ug/ml (100ul/well) on the plate. Dose response curve for Anti-GPRC5D Antibody, hFc Tag with the EC50 of 4.9ng/ml determined by ELISA (QC Test).
The purity of FITC-equivalent Human GPRC5D VLP is greater than 95% as determined by SEC-HPLC. The purity of FITC-equivalent Human GPRC5D VLP is greater than 95% as determined by SEC-HPLC.
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