Name: Human B7-H4 Protein (BH7-HM104)
Brand: KactusBio
SKU: BH7-HM104-100UG
Price: 210.0 USD
Availability: InStock

Express System: HEK293
Product Tag: C-His
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: Immobilized Human B7-H4, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-B7-H4 Antibody, hFc Tag with the EC50 of 8.6ng/ml determined by ELISA. See testing image for detail.
Amino Acid Range: Phe29-Ala258

Catalog #BH7-HM104

Size

100UG

500UG

Order now, ships by:

Human B7-H4 Protein (BH7-HM104) Summary

Product Description	Recombinant Human B7-H4 Protein is expressed from HEK293 with His tag at the C-terminus.It contains Phe29-Ala258.
Product Background	B7-H4, also known as B7x and B7S1, is a 50-80 kDa glycosylated member of the B7 family of immunomodulatory proteins. B7-H4 is up-regulated in several carcinomas in correlation with tumor progression and metastasis. A soluble form of B7-H4 is elevated in the serum of ovarian cancer, renal cell carcinoma, and rheumatoid arthritis patients, also in correlation with advanced disease status-.
Product Category	Recombinant Protein / Antibody discovery / Immune checkpoint proteins

Human B7-H4 Protein (BH7-HM104) Specifications/Details

Protein	B7-H4
Synonyms	B7H4; B7-H4; B7S1; B7h.5; B7x; FLJ22418; VTCN1; PRO1291
Accession	Q7Z7D3-1
Species	Human
Biotinylated	no
Amino Acid Range	Phe29-Ala258
Molecular Weight	The protein has a predicted MW of 26.92 kDa. Due to glycosylation, the protein migrates to 50-65 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Human B7-H4, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-B7-H4 Antibody, hFc Tag with the EC50 of 8.6ng/ml determined by ELISA. See testing image for detail.
Product Tag	C-His
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 0.1 EU per ug by the LAL method.

Form	Liquid
Shipping	Shipped with dry ice.
Formulation	Supplied as 0.22 um filtered solution in PBS (pH 7.4).
Stability And Storage	Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Human B7-H4, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-B7-H4 Antibody, hFc Tag with the EC50 of 8.6ng/ml determined by ELISA.
	Human B7-H4 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	Loaded Anti-B7-H4 Antibody, hFc Tag on ProA-Biosensor can bind Human B7-H4, His Tag with an affinity constant of 8.62 nM as determined in BLI assay (Gator® Prime).
	The purity of Human B7-H4 is greater than 95% as determined by SEC-HPLC.