Name: Human CHRDL1 Protein (CDL-HE101)
Brand: KactusBio
SKU: CDL-HE101-100UG
Price: 363.0 USD
Availability: InStock

Express System: E.coli
Product Tag: N-His
Purity: > 90% as determined by Bis-Tris PAGE
Activity: Immobilized Human CHRDL1, His Tag at 1ug/ml (100ul/Well) on the plate. Dose response curve for Anti-CHRDL1 Antibody, hFc Tag with the EC50 of 6.7ng/ml determined by ELISA (QC Test). See testing image for detail.
Amino Acid Range: Glu28-Cys456

Catalog #CDL-HE101

Size

100UG

500UG

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Product Description	Recombinant Human CHRDL1 Protein is expressed from E.coli with His tag at the N-Terminus.It contains Glu28-Cys456.
Product Background	CHRDL1 (Chordin-like 1) is a secreted protein that acts as an antagonist of bone morphogenetic protein (BMP). BMP plays a role as an activator of BMP receptor II (BMPR II), which mediates extracellular to intracellular signal transmission and is involved in carcinogenesis and metastasis.The hypermethylation of the CHRDL1 promoter in gastric cancer, which induced low expression of CHRDL1 and decreased its secretion to the supernatant.
Product Category	Recombinant Protein / Antibody discovery / Antibody discovery \| Others

Protein	CHRDL1
Synonyms	Neuralin-1; Neurogenesin-1; Ventroptin; CHRDL1; NRLN1; CHL; Chordin-like 1; CRDL1; dA141H5.1; VOPT
Accession	Q9BU40-1
Species	Human
Biotinylated	no
Amino Acid Range	Glu28-Cys456
Molecular Weight	The protein has a predicted MW of 50 kDa same as Bis-Tris PAGE result.
Activity	Immobilized Human CHRDL1, His Tag at 1ug/ml (100ul/Well) on the plate. Dose response curve for Anti-CHRDL1 Antibody, hFc Tag with the EC50 of 6.7ng/ml determined by ELISA (QC Test). See testing image for detail.
Product Tag	N-His
Expression System	E.coli
Purity	> 90% as determined by Bis-Tris PAGE
Endotoxin	Less than 1 EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in 4mM HCl. Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Dissolve the lyophilized protein in 4mM HCL. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Human CHRDL1, His Tag at 1ug/ml (100ul/Well) on the plate. Dose response curve for Anti-CHRDL1 Antibody, hFc Tag with the EC50 of 6.7ng/ml determined by ELISA (QC Test).
	Human CHRDL1 on Bis-Tris PAGE under reduced condition. The purity is greater than 90%.