Product Description |
Recombinant Human Complement component 3 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ser23-Asn1663. |
Product Background |
Complement component 3 (C3), a pivotal molecule in the complement system, is an essential immune mediator in various diseases, including psoriasis. C3 deficiency promoted imiquimod-induced skin cell apoptosis and supported greater proportions of IFN-γ T cells in the inflamed tissues. |
Product Category |
Recombinant Protein |
Target |
Complement component 3 |
Synonyms |
Complement C3；HSE-MSF；C3；CPAMD1；AHUS5；ARMD9；ASP；C3a；C3b；HEL-S-62p |
Accession |
|
Species |
Human |
Biotinylated |
no |
Amino Acid Range |
Ser23-Asn1663 |
Molecular Weight |
The protein has a predicted MW of 188.52 kDa. Due to enzyme lysis and glycosylation, the protein migrates to 67-68 kDa, 110-115 kDa and 140-160 kDa based on Bis-Tris PAGE result. |
Product Tag |
C-His |
Express System |
HEK293 |
Purity |
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
Endotoxin |
Less than 1EU per ug by the LAL method. |
Form |
Lyophilized |
Shipping |
Shipped at ambient temperature. |
Formulation |
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution |
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
Stability And Storage |
Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
|
|
Human Complement component 3 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. |
|
|
The purity of Human Complement component 3 is greater than 95% as determined by SEC-HPLC. |
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