Human DSG-2/Desmoglein-2 Protein (DSG-HM102)
Human DSG-2/Desmoglein-2 Protein (DSG-HM102)
Human DSG-2/Desmoglein-2 Protein (DSG-HM102)
Human DSG-2/Desmoglein-2 Protein (DSG-HM102)
  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Bis-Tris PAGE
  • Activity: Immobilized Human DSG-2, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-DSG-2 Antibody, hFc Tag with the EC50 of 7.9ng/ml determined by ELISA (QC Test). See testing image for detail.
  • Amino Acid Range: Ala50-Gly609
Catalog #DSG-HM102
Regular price $297.00
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Product Description

Recombinant Human DSG-2/Desmoglein-2 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ala50-Gly609.

Product Background

Desmoglein-2 (DSG-2) as the primary high-affinity receptor used by adenoviruses Ad3, Ad7, Ad11 and Ad14. These serotypes represent key human pathogens causing respiratory and urinary tract infections. In epithelial cells, adenovirus binding of DSG-2 triggers events reminiscent of epithelial-to-mesenchymal transition, leading to transient opening of intercellular junctions.

Product Category

Recombinant Protein / Antibody discovery / Antibody discovery | Others
Protein
DSG-2/Desmoglein-2
Synonyms
Desmoglein-2; HDGC; DSG2; CDHF5; ARVC10; CMD1BB; MGC117036; MGC117037
Accession
Species
Human
Biotinylated
no
Amino Acid Range
Ala50-Gly609
Molecular Weight
The protein has a predicted MW of 63.6 kDa. Due to glycosylation, the protein migrates to 75-80 kDa based on Bis-Tris PAGE result.
Activity
Immobilized Human DSG-2, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-DSG-2 Antibody, hFc Tag with the EC50 of 7.9ng/ml determined by ELISA (QC Test). See testing image for detail.

Product Tag

C-His
Expression System
HEK293
Purity
> 95% as determined by Bis-Tris PAGE
Endotoxin
Less than 1 EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage
-20 to -80°C for 12 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Immobilized Human DSG-2, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-DSG-2 Antibody, hFc Tag with the EC50 of 7.9ng/ml determined by ELISA (QC Test). Immobilized Human DSG-2, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-DSG-2 Antibody, hFc Tag with the EC50 of 7.9ng/ml determined by ELISA (QC Test).
Human DSG-2 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Human DSG-2 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
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