Name: Human GAS6 Protein (GAS-HM116)
Brand: KactusBio
SKU: GAS-HM116-100UG
Price: 412.5 USD
Availability: InStock

Express System: HEK293
Product Tag: C-His
Purity: > 95% as determined by Bis-Tris PAGE;> 90% as determined by HPLC
Activity: Immobilized Human GAS6, His Tag at 5 ug/ml (100 ul/well) on the plate. Dose response curve for Human Axl, hFc Tag with the EC50 of 3.4 ng/ml determined by ELISA (QC Test). The affinity constant of 2.36 uM as determined in SPR assay (Biacore T200). See testing image for detail.
Amino Acid Range: Ala49-Ala678

Catalog #GAS-HM116

Size

100UG

500UG

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Product Description	Recombinant Human GAS6 Protein is expressed from HEK293 with His tag at the C-Terminus.; It contains Ala49-Ala678.
Product Background	Growth arrest-specific 6, also known as Gas6, is a human gene encoding the Gas6 protein, which was originally found to be upregulated in growth-arrested fibroblasts. Gas6 is a member of the vitamin K-dependent family of proteins expressed in many human tissues and regulates several biological processes in cells, including proliferation, survival and migration, by binding to its receptors Tyro3, Axl and Mer (TAM).
Product Category	Recombinant Protein / Antibody discovery / Antibody discovery \| Others

Protein	GAS6
Synonyms	GAS-6; AXLLG; GAS6; DKFZp666G247; FLJ34709
Accession	Q14393-2
Species	Human
Biotinylated	no
Amino Acid Range	Ala49-Ala678
Molecular Weight	The protein has a predicted MW of 70.60 kDa. Due to glycosylation, the protein migrates to 71-75 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Human GAS6, His Tag at 5 ug/ml (100 ul/well) on the plate. Dose response curve for Human Axl, hFc Tag with the EC50 of 3.4 ng/ml determined by ELISA (QC Test). The affinity constant of 2.36 uM as determined in SPR assay (Biacore T200). See testing image for detail.
Product Tag	C-His
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 90% as determined by HPLC
Endotoxin	Less than 1 EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22 um filtered solution in 20 mM Tris, 500 mM NaCl (pH 8.5). Normally 8% mannitol is added as protectant before lyophilization.
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Human GAS6, His Tag immobilized on CM5 Chip can bind Human TYRO3, His Tag with an affinity constant of 2.36 uM as determined in SPR assay (Biacore T200).
	Immobilized Human GAS6, His Tag at 5 ug/ml (100 ul/well) on the plate. Dose response curve for Human Axl, hFc Tag with the EC50 of 3.4 ng/ml determined by ELISA (QC Test).
	Immobilized Human MERTK, mFc Tag at 5ug/ml(100ul/well) on the plate. Dose response curve for Human GAS6, His Tag with the EC50 of 3.55ug/ml determined by ELISA.
	Immobilized Human GAS6, His Tag at 5 ug/ml (100 ul/well) on the plate. Dose response curve for Anti-GAS6 Antibody, hFc Tag with the EC50 of 12.3 ng/ml determined by ELISA.
	Human GAS6 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Human GAS6 is greater than 90% as determined by SEC-HPLC.