Name: Human GITR Ligand/TNFSF18 Trimer Protein (FSF-HM418)
Brand: KactusBio
SKU: FSF-HM418-100UG
Price: 297.0 USD
Availability: InStock

Human GITR Ligand/TNFSF18 Trimer Protein (FSF-HM418)

Immobilized Human GITR Ligand Trimer, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Human GITR, hFc Tag with the EC50 of 50.8ng/ml determined by ELISA.

Human GITR Ligand Trimer on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

The purity of Human GITR Ligand Trimer is greater than 95% as determined by SEC-HPLC.

Express System: HEK293
Product Tag: N-His-Flag
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: Immobilized Human GITR Ligand Trimer, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Human GITR, hFc Tag with the EC50 of 50.8ng/ml determined by ELISA. See testing image for detail.
Amino Acid Range: Gln50-Ser177

Catalog #FSF-HM418

Size

100UG

500UG

Order now, ships by:

[{"id":42618357874910,"title":"100UG","option1":"100UG","option2":null,"option3":null,"sku":"FSF-HM418-100UG","requires_shipping":true,"taxable":true,"featured_image":null,"available":true,"name":"Human GITR Ligand\/TNFSF18 Trimer Protein (FSF-HM418) - 100UG","public_title":"100UG","options":["100UG"],"price":29700,"weight":5,"compare_at_price":null,"inventory_management":"shopify","barcode":null,"requires_selling_plan":false,"selling_plan_allocations":[],"quantity_rule":{"min":1,"max":null,"increment":1}},{"id":43584292716766,"title":"500UG","option1":"500UG","option2":null,"option3":null,"sku":"FSF-HM418-500UG","requires_shipping":true,"taxable":true,"featured_image":null,"available":true,"name":"Human GITR Ligand\/TNFSF18 Trimer Protein (FSF-HM418) - 500UG","public_title":"500UG","options":["500UG"],"price":99000,"weight":5,"compare_at_price":null,"inventory_management":"shopify","barcode":null,"requires_selling_plan":false,"selling_plan_allocations":[],"quantity_rule":{"min":1,"max":null,"increment":1}}]

Product Description	Recombinant Human GITR Ligand/TNFSF18 Trimer Protein is expressed from HEK293 with His tag and flag tag at the N-Terminus.It contains Gln50-Ser177 trimer design.
Product Background	Glucocorticoid-induced TNFR-related protein (TNFRSF18, GITR, CD357), expressed by T cells, and its ligand (TNFSF18, GITRL), expressed by myeloid populations, provide co-stimulatory signals that boost T cell activity. Due to the important role that GITR plays in regulating immune functions, agonistic stimulation of GITR is a promising therapeutic concept.
Product Category	Recombinant Protein / Antibody discovery / Immune checkpoint proteins

Protein	GITR Ligand/TNFSF18
Synonyms	TNFSF18; AITRL; TL6; GITRL; GITR Ligand
Accession	Q9UNG2
Species	Human
Biotinylated	no
Amino Acid Range	Gln50-Ser177
Molecular Weight	The protein has a predicted MW of 47.5 kDa. Due to glycosylation, the protein migrates to 50-70 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Human GITR Ligand Trimer, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Human GITR, hFc Tag with the EC50 of 50.8ng/ml determined by ELISA. See testing image for detail.
Product Tag	N-His-Flag
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1 EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Human GITR Ligand Trimer, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Human GITR, hFc Tag with the EC50 of 50.8ng/ml determined by ELISA.
	Human GITR Ligand Trimer on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Human GITR Ligand Trimer is greater than 95% as determined by SEC-HPLC.

Product Description

Product Background

Product Category

Product Tag