Human IFN gamma R1/IFNGR1 Protein (IFN-HM2GR)

Immobilized Human IFN gamma, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Human IFN gamma R1, hFc Tag with the EC50 of 4.6ng/ml determined by ELISA.

Human IFNGR1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

The purity of Human IFN gamma R1 is greater than 95% as determined by SEC-HPLC.

Express System: HEK293
Product Tag: C-hFc (IgG1)
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: Immobilized Human IFN gamma, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Human IFN gamma R1, hFc Tag with the EC50 of 4.6ng/ml determined by ELISA.
Amino Acid Range: Glu18-Gly245

Catalog #IFN-HM2GR

Price

$165⁰⁰

Size

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Human IFN gamma R1/IFNGR1 Protein (IFN-HM2GR) Summary

Product Description

Recombinant Human IFN gamma R1/IFNGR1 Protein is expressed from HEK293 with hFc (IgG1) tag at the C-Terminus.It contains Glu18-Gly245.

Product Background

IFN-gamma and one of its receptor subunits, IFNGR1, are translocated to the nucleus, together with STAT1alpha as one macromolecular complex, via the classical importin-dependent pathway.Put IFN-gamma and its receptor subunit, IFNGR1, in direct contact with the promoter region of IFN-gamma-activated genes with associated increased activity, thus suggesting a transcriptional/cotranscriptional role for IFN-gamma/IFNGR1 as well as a possible role in determining the specificity of IFN-gamma action.

Human IFN gamma R1/IFNGR1 Protein (IFN-HM2GR) Specifications/Details

Protein	IFN gamma R1/IFNGR1
Synonyms	IFN-gamma-R1; CDw119; CD119; IFNGR1; IFNGR; AVP; FLJ45734; IFN-gamma R1; IFN-gR1; type 2; IFNγ; IFNγR1; IFN γR1; IFNγ R1; IFN γ R1;IFNg; IFN gamma; IFN gamma R1; IFN gR1; IFNg R1; IFN g R1
Accession	AAH05333
Species	Human
Biotinylated	no
Amino Acid Range	Glu18-Gly245
Molecular Weight	The protein has a predicted MW of 52.4 kDa. Due to glycosylation, the protein migrates to 60-75 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Human IFN gamma, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Human IFN gamma R1, hFc Tag with the EC50 of 4.6ng/ml determined by ELISA.
Product Tag	C-hFc (IgG1)
Fluorophore	Unconjugated
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 24 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

	Immobilized Human IFN gamma, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Human IFN gamma R1, hFc Tag with the EC50 of 4.6ng/ml determined by ELISA.
	Human IFNGR1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Human IFN gamma R1 is greater than 95% as determined by SEC-HPLC.