Human IFN gamma R1/IFNGR1 Protein (IFN-HM2GR)
Human IFN gamma R1/IFNGR1 Protein (IFN-HM2GR)
Human IFN gamma R1/IFNGR1 Protein (IFN-HM2GR)
Human IFN gamma R1/IFNGR1 Protein (IFN-HM2GR)
  • Express System: HEK293
  • Product Tag: C-hFc
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Activity: Immobilized Human IFN gamma, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Human IFN gamma R1, hFc Tag with the EC50 of 4.6ng/ml determined by ELISA. See testing image for detail.
  • Amino Acid Range: Glu18-Gly245
Catalog #IFN-HM2GR
Regular price $165.00
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Product Description

Recombinant Human IFN gamma R1/IFNGR1 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Glu18-Gly245.

Product Background

IFN-gamma and one of its receptor subunits, IFNGR1, are translocated to the nucleus, together with STAT1alpha as one macromolecular complex, via the classical importin-dependent pathway.Put IFN-gamma and its receptor subunit, IFNGR1, in direct contact with the promoter region of IFN-gamma-activated genes with associated increased activity, thus suggesting a transcriptional/cotranscriptional role for IFN-gamma/IFNGR1 as well as a possible role in determining the specificity of IFN-gamma action.

Product Category

Recombinant Protein / Antibody discovery / Antibody discovery | Others
Protein
IFN gamma R1/IFNGR1
Synonyms
IFN-gamma-R1; CDw119; CD119; IFNGR1; IFNGR; AVP; FLJ45734; IFN-gamma R1; IFN-gR1; type 2; IFNγ; IFNγR1; IFN γR1; IFNγ R1; IFN γ R1
Accession
Species
Human
Biotinylated
no
Amino Acid Range
Glu18-Gly245
Molecular Weight
The protein has a predicted MW of 52.4 kDa. Due to glycosylation, the protein migrates to 60-75 kDa based on Bis-Tris PAGE result.
Activity
Immobilized Human IFN gamma, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Human IFN gamma R1, hFc Tag with the EC50 of 4.6ng/ml determined by ELISA. See testing image for detail.

Product Tag

C-hFc
Expression System
HEK293
Purity
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin
Less than 1 EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage
-20 to -80°C for 24 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Immobilized Human IFN gamma, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Human IFN gamma R1, hFc Tag with the EC50 of 4.6ng/ml determined by ELISA. Immobilized Human IFN gamma, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Human IFN gamma R1, hFc Tag with the EC50 of 4.6ng/ml determined by ELISA.
Human IFNGR1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Human IFNGR1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Human IFN gamma R1 is greater than 95% as determined by SEC-HPLC. The purity of Human IFN gamma R1 is greater than 95% as determined by SEC-HPLC.
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