Human IL-1F10/IL-38-Protein (ILF-HE138)
Human IL-1F10/IL-38-Protein (ILF-HE138)
  • Express System: E.coli
  • Product Tag: C-His
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Amino Acid Range: Met1-Trp152
Catalog #ILF-HE138
Regular price $346.50
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Product Description

Recombinant Human IL-1F10/IL-38-Protein is expressed from E.coli with His tag at the C-Terminus.It contains Met1-Trp152.

Product Background

Interleukin (IL)-38, a newly discovered IL-1 family cytokine, is expressed in several tissues and secreted by various cells. IL-38 has recently been reported to exert an anti-inflammatory function by binding to several receptors, including interleukin-36 receptor (IL-36R), interleukin-1 receptor accessory protein-like 1 (IL-1RAPL1), and interleukin-1 receptor 1 (IL-1R1) to block binding with other pro-inflammatory cytokines and inhibit subsequent signaling pathways; thereby regulating the differentiation and function of T cells, peripheral blood mononuclear cells, macrophages, and dendritic cells.

Product Category

Recombinant Protein / Antibody discovery / Antibody discovery | Others
Protein
IL-1F10/IL-38
Synonyms
FIL1 theta; IL-1HY2; IL-1 theta; IL38;
Accession
Species
Human
Biotinylated
no
Amino Acid Range
Met1-Trp152
Molecular Weight
The protein has a predicted MW of 18.64 kDa. The protein migrates to 20-25 kDa based on Bis-Tris PAGE result.

Product Tag

C-His
Expression System
E.coli
Purity
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin
Less than 1 EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage
-20 to -80°C for 12 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Human IL-1F10 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Human IL-1F10 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Human IL-1F10 is greater than 95% as determined by SEC-HPLC. The purity of Human IL-1F10 is greater than 95% as determined by SEC-HPLC.
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