Human IL-1F10/IL-38-Protein (ILF-HY138)
  • Express System: Yeast
  • Product Tag: C-His
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Activity: The affinity constant of 35.38 uM as determined in SPR assay (Biacore T200). See testing image for detail.
  • Amino Acid Range: Met1-Trp152
Catalog #ILF-HY138
Regular price $240.00
/
Size

Order now, ships by:

Product Description
Recombinant Human IL-1F10/IL-38-Protein is expressed from Yeast with His tag at the C-terminus.It contains Met1-Trp152.
Product Background
Interleukin (IL)-38, a newly discovered IL-1 family cytokine, is expressed in several tissues and secreted by various cells. IL-38 has recently been reported to exert an anti-inflammatory function by binding to several receptors, including interleukin-36 receptor (IL-36R), interleukin-1 receptor accessory protein-like 1 (IL-1RAPL1), and interleukin-1 receptor 1 (IL-1R1) to block binding with other pro-inflammatory cytokines and inhibit subsequent signaling pathways; thereby regulating the differentiation and function of T cells, peripheral blood mononuclear cells, macrophages, and dendritic cells.
Product Category
Recombinant Protein
Target
IL-1F10/IL-38
Accession
Species
Human
Biotinylated
no
Amino Acid Range
Met1-Trp152
Molecular Weight
The protein has a predicted MW of 18.07 kDa. Due to glycosylation, the protein migrates to 20-23 kDa based on Bis-Tris PAGE result.
Activity
The affinity constant of 35.38 uM as determined in SPR assay (Biacore T200). See testing image for detail.
Product Tag
C-His
Express System
Yeast
Purity
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin
Less than 1EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage
Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Human IL-1 Rrp-2, hFc Tag captured on CM5 Chip via Protein A can bind Human IL-1F10, His Tag with an affinity constant of 35.38 uM as determined in SPR assay (Biacore T200).
Human IL-1F10 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Human IL-1F10 is greater than 95% as determined by SEC-HPLC.

Have more questions?

Check out our Frequently Asked Questions page for more details about product specifications, ordering, and shipments.

Contact Us

support@kactusbio.us

Recently viewed