Name: Human IL-7 R alpha&TSLPR Protein (ILT-HM107)
Brand: KactusBio
SKU: ILT-HM107-100UG
Price: 379.5 USD
Availability: InStock

Sensorgram showing binding kinetics of biomolecular interaction using SPR, with multi-concentration response curves over time.

Human IL-7R alpha&TSLPR, His Tag captured on CM5 Chip via Anti-His Antibody can bind Human IL-7, No Tag with an affinity constant of 15.54 nM as determined in SPR assay (Biacore T200).

Immobilized Human IL-7R alpha&TSLPR, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Human TSLP, hFc Tag with the EC50 of 3.8ng/ml determined by ELISA (QC Test).

Human IL-7 R alpha&TSLPR on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

Loaded Human TSLP, Fc Tag on ProA-Biosensor can bind IL-7 R alpha&TSLP R, His Tag with an affinity constant of 0.37 nM as determined in BLI assay (Gator® Prime).

The purity of Human IL-7 R alpha&TSLPR is greater than 95% as determined by SEC-HPLC.

Express System: HEK293
Product Tag: C-His
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: Immobilized Human IL-7R alpha&TSLPR, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Human TSLP, hFc Tag with the EC50 of 3.8ng/ml determined by ELISA (QC Test). The affinity constant of 15.54 nM as determined in SPR assay (Biacore T200). See testing image for detail.
Amino Acid Range: Glu21-Asp239(IL-7 R alpha) & Gln23-Lys231(TSLPR)

Catalog #ILT-HM107

Size

100UG

500UG

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Product Description	Recombinant Human IL-7 R alpha&TSLPR Protein is expressed from HEK293 with His tag at the C-terminus of IL-7 R alpha.It contains Glu21-Asp239 (IL-7 R alpha) and Gln23-Lys231 (TSLPR).
Product Background	IL-7R alpha & TSLPR is an heterodimeric receptor, with TSLP as the ligand, which initiates downstream signaling pathways upon binding to TSLP and subsequently participates in thymus development and immune cell generation. Among them, IL-7R alpha is a component of both the IL-7 and TSLP receptors.
Product Category	Recombinant Protein / Antibody discovery / Antibody discovery \| Others

Protein	IL-7 R alpha&TSLPR
Synonyms	IL7Ra; CD127; TSLP R; CRLF2; IL-XR; ILXR; p2RY8; TSLPR; CRL2; CRLF2Y
Accession	P16871-1(IL-7 R alpha)&Q9HC73-1(TSLPR)
Species	Human
Biotinylated	no
Amino Acid Range	Glu21-Asp239(IL-7 R alpha) & Gln23-Lys231(TSLPR)
Molecular Weight	The protein has a predicted MW of 31.18 kDa (IL-7 R alpha) and 29.03 kDa (TSLPR). Due to glycosylation, the protein migrates to 58-68 kDa (IL-7 R alpha) and 50-58 kDa (TSLPR) based on Bis-Tris PAGE result.
Activity	Immobilized Human IL-7R alpha&TSLPR, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Human TSLP, hFc Tag with the EC50 of 3.8ng/ml determined by ELISA (QC Test). The affinity constant of 15.54 nM as determined in SPR assay (Biacore T200). See testing image for detail.
Product Tag	C-His
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1 EU per ug by the LAL method.

Form	Liquid
Shipping	Shipped with dry ice.
Formulation	Supplied as 0.22 um filtered solution in PBS (pH 7.4).
Stability And Storage	Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Human IL-7R alpha&TSLPR, His Tag captured on CM5 Chip via Anti-His Antibody can bind Human IL-7, No Tag with an affinity constant of 15.54 nM as determined in SPR assay (Biacore T200).
	Immobilized Human IL-7R alpha&TSLPR, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Human TSLP, hFc Tag with the EC50 of 3.8ng/ml determined by ELISA (QC Test).
	Human IL-7 R alpha&TSLPR on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	Loaded Human TSLP, Fc Tag on ProA-Biosensor can bind IL-7 R alpha&TSLP R, His Tag with an affinity constant of 0.37 nM as determined in BLI assay (Gator® Prime).
	The purity of Human IL-7 R alpha&TSLPR is greater than 95% as determined by SEC-HPLC.

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