Human ILDR2 Protein (ILD-HM202)
Human ILDR2 Protein (ILD-HM202)
  • Express System: HEK293
  • Product Tag: C-hFc
  • Purity: > 95% as determined by Bis-Tris PAGE;> 90% as determined by HPLC
  • Amino Acid Range: Leu21-Met184
Catalog #ILD-HM202
Regular price $412.50
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Product Description

Recombinant Human ILDR2 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Leu21-Met184.

Product Background

Ildr2, a modifier of diabetes susceptibility in obese mice, is expressed in most organs, including islets and hypothalamus, with reduced levels in livers of diabetes-susceptible B6.DBA mice congenic for a 1.8 Mb interval of Chromosome 1. In hepatoma and neuronal cells, ILDR2 is primarily located in the endoplasmic reticulum membrane. Livers in knockdown mice were steatotic, with increased hepatic and circulating triglycerides and total cholesterol. Increased circulating VLDL, without reduction in triglyceride clearance suggests an effect of reduced hepatic ILDR2 on hepatic cholesterol clearance.

Product Category

Recombinant Protein / Antibody discovery / Antibody discovery | Others
Protein
ILDR2
Synonyms
ILDR2; C1orf32; dJ782G3.1; RP4-782G3.2
Accession
Species
Human
Biotinylated
no
Amino Acid Range
Leu21-Met184
Molecular Weight
The protein has a predicted MW of 35 kDa. Due to glycosylation, the protein migrates to 48-55 kDa based on Bis-Tris PAGE result.

Product Tag

C-hFc
Expression System
HEK293
Purity
> 95% as determined by Bis-Tris PAGE;> 90% as determined by HPLC
Endotoxin
Less than 1 EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage
-20 to -80°C for 12 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Human ILDR2 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Human ILDR2 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Human ILDR2 is greater than 90% as determined by SEC-HPLC. The purity of Human ILDR2 is greater than 90% as determined by SEC-HPLC.
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