Human Integrin alpha V beta 3 (ITGAV&ITGB3) Heterodimer Protein (ITG-HM2V3)
Human Integrin alpha V beta 3 (ITGAV&ITGB3) Heterodimer Protein (ITG-HM2V3)
  • Express System: HEK293
  • Product Tag: C-hFc
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Activity: Immobilized Human ITGAV&ITGB3, hFc Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Anti-alpha V beta3 Antibody, hFc Tag with the EC50 of 16.9ng/ml determined by ELISA. See testing image for detail.
  • Amino Acid Range: Phe31-Val992(ITGAV) acidic tail & Gly27-Asp718(ITGB3) basic tail
Catalog #ITG-HM2V3
Regular price $375.00
/
Size

Order now, ships by:

Product Description

Recombinant Human Integrin alpha V beta 3 (ITGAV&ITGB3) Heterodimer Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Phe31-Val992(ITGAV) acidic tail & Gly27-Asp718(ITGB3) basic tail.

Product Background

ITGAV&ITGB3 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling. ITGAV&ITGB3 binds to FGF1 and this binding is essential for FGF1 signaling. ITGAV&ITGB3 binds to FGF2 and this binding is essential for FGF2 signaling. ITGAV&ITGB3 binds to IGF1 and this binding is essential for IGF1 signaling. ITGAV&ITGB3 binds to IGF2 and this binding is essential for IGF2 signaling.

Product Category

Recombinant Protein / Antibody discovery

Protein

Integrin alpha V beta 3 (ITGAV&ITGB3) Heterodimer

Synonyms

αVβ3; Integrin alpha V beta 3; beta3; alphaV; ITGAV&ITGB3;Integrin alpha V β 3; β3

Accession

Species

Human

Biotinylated

no

Amino Acid Range

Phe31-Val992(ITGAV) acidic tail & Gly27-Asp718(ITGB3) basic tail

Molecular Weight

The protein has a predicted MW of 131.90 kDa (ITGAV) & 101.79 kDa (ITGB3). Due to glycosylation, the protein migrates to 140-160 kDa (ITGAV) & 105-130 kDa (ITGB3) based on Bis-Tris PAGE result.

Activity

Immobilized Human ITGAV&ITGB3, hFc Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Anti-alpha V beta3 Antibody, hFc Tag with the EC50 of 16.9ng/ml determined by ELISA. See testing image for detail.

Product Tag

C-hFc

Expression System

HEK293

Purity

> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC

Endotoxin

Less than 1EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage
-20 to -80°C for 12 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Immobilized Human ITGAV&ITGB3, hFc Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Anti-alpha V beta3 Antibody, hFc Tag with the EC50 of 16.9ng/ml determined by ELISA. Immobilized Human ITGAV&ITGB3, hFc Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Anti-alpha V beta3 Antibody, hFc Tag with the EC50 of 16.9ng/ml determined by ELISA.
Human ITGAV&ITGB3 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Human ITGAV&ITGB3 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Human ITGAV&ITGB3 is greater than 95% as determined by SEC-HPLC. The purity of Human ITGAV&ITGB3 is greater than 95% as determined by SEC-HPLC.

Have more questions?

Check out our Frequently Asked Questions page for more details about product specifications, ordering, and shipments.

Contact Us

support@kactusbio.us

Recently viewed