Name: Human LGR-4 Protein-Nanodisc (LGR-HM10N)
Brand: KactusBio
SKU: LGR-HM10N-100UG
Price: 1210.0 USD
Availability: InStock

Express System: HEK293
Product Tag: C-His
Activity: Immobilized Human R-Spondin 3, hFc Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Human LGR-4 Nanodisc, His Tag with the EC50 of 0.36ug/ml determined by ELISA (QC Test). The affinity constant of 0.40 nM as determined in SPR assay (Biacore T200). See testing image for detail.
Amino Acid Range: Met1-Asp951

Catalog #LGR-HM10N

Size

100UG

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Product Description	Recombinant Human LGR-4 Protein-Nanodisc is expressed from HEK293 with His tag at the C-terminus.It contains Met1-Asp951.
Product Background	Leucine-rich repeat-containing G protein-coupled receptor (LGR)-4 is a G protein-coupled receptor (GPCR) with a seven-transmembrane domain structure. LGRs are evolutionally and structurally phylogenetic, classified into three subgroups and are members of the so-called orphan receptors.
Product Category	Recombinant Protein / Antibody discovery / Multiple transmembrane proteins / Nanodisc

Protein	LGR-4
Synonyms	LGR4; GPR48
Accession	Q9BXB1-1
Species	Human
Biotinylated	no
Amino Acid Range	Met1-Asp951
Molecular Weight	The protein has a predicted MW of 105.80 kDa.
Activity	Immobilized Human R-Spondin 3, hFc Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Human LGR-4 Nanodisc, His Tag with the EC50 of 0.36ug/ml determined by ELISA (QC Test). The affinity constant of 0.40 nM as determined in SPR assay (Biacore T200). See testing image for detail.
Product Tag	C-His
Expression System	HEK293
Endotoxin	Less than 1 EU per ug by the LAL method.

Form	Liquid
Shipping	Shipped with dry ice.
Formulation	Supplied as 0.22 um filtered solution in PBS (pH 7.4). Notice: Not recommended for flow cytometry in mammalian cells.
Stability And Storage	Valid for 6 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Human R Spondin 3, His Tag immobilized on CM5 Chip can bind Human LGR-4 Nanodisc, His Tag with an affinity constant of 0.40 nM as determined in SPR assay (Biacore T200).
	Immobilized Human R-Spondin 3, hFc Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Human LGR-4 Nanodisc, His Tag with the EC50 of 0.36ug/ml determined by ELISA (QC Test).