Human RET-Protein (RET-HM101) Summary
Product Description |
Recombinant Human RET-Protein is expressed from HEK293 with His tag at the C-Terminus.; It contains Leu29-Arg635. |
Product Background |
RET is a proto-oncogene encoding a receptor tyrosine kinase. RET regulates key aspects of cellular proliferation, differentiation and survival. The activation of RET via gene fusions or point mutations is closely related to lung, thyroid and other cancers. |
Product Category |
Recombinant Protein / Antibody discovery / Antibody discovery | Others |
Human RET-Protein (RET-HM101) Specifications/Details
Protein |
RET |
Synonyms |
Cadherin family member 12; CDHF12; CDHR16; PTC; RET51; HSCR1; MTC1; RET-ELE1; RET51 |
Accession |
|
Species |
Human |
Biotinylated |
no |
Amino Acid Range |
Leu29-Arg635 |
Molecular Weight |
The protein has a predicted MW of 68.87 kDa. Due to glycosylation, the protein migrates to 90-120 kDa based on Bis-Tris PAGE result. |
Product Tag |
C-His |
Expression System |
HEK293 |
Purity |
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
Endotoxin |
Less than 1 EU per ug by the LAL method. |
Form |
Lyophilized |
Shipping |
Shipped at ambient temperature. |
Formulation |
Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution |
Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking. |
Stability And Storage |
-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
|
|
Human RET-on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. |
|
|
The purity of Human RET is greater than 95% as determined by SEC-HPLC. |
Related Products
Have more questions?
Check out our Frequently Asked Questions page for more details about product specifications, ordering, and shipments.
Contact Us
More from Antibody Drug Discovery Proteins
Recently viewed
