Name: Human Siglec-6/CD327 Protein (SIG-HM406)
Brand: KactusBio
SKU: SIG-HM406-100UG
Price: 346.5 USD
Availability: InStock

Express System: HEK293
Product Tag: C-His-Avi
Purity: >95% as determined by Bis-Tris PAGE
Activity: Immobilized Human Siglec-6, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-Siglec-6 Antibody, hFc Tag with the EC50 of 3.8ng/ml determined by ELISA (QC Test). The affinity constant of 0.16 nM as determined in SPR assay (Biacore T200). See testing image for detail.
Amino Acid Range: Gln27-Val331

Catalog #SIG-HM406

Size

100UG

500UG

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Product Description	Recombinant Human Siglec-6/CD327 Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Gln27-Val331.
Product Background	Siglecs (Sialic acid binding Ig-like Lectins) are I-type (Ig-type) lectins that belong to the Ig superfamily. They are characterized by an N-terminal Ig-like V-type domain which mediates sialic acid binding, followed by varying numbers of Ig-like C2-type domains. Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface.
Product Category	Recombinant Protein / Antibody discovery

Protein	Siglec-6
Synonyms	CD327; CD33 antigen-like 1; CD33L1; CDw327; OB-BP1; Siglec-6; SIGLEC6; CD33L; OBBP1
Accession	O43699-3
Species	Human
Biotinylated	no
Amino Acid Range	Gln27-Val331
Molecular Weight	The protein has a predicted MW of 36.6 kDa. Due to glycosylation, the protein migrates to 55-70 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Human Siglec-6, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-Siglec-6 Antibody, hFc Tag with the EC50 of 3.8ng/ml determined by ELISA (QC Test). The affinity constant of 0.16 nM as determined in SPR assay (Biacore T200). See testing image for detail.
Product Tag	C-His-Avi
Expression System	HEK293
Purity	>95% as determined by Bis-Tris PAGE
Endotoxin	Less than 1 EU per ug by the LAL method.

Form	Liquid
Shipping	Shipped with dry ice.
Formulation	Supplied as 0.22 um filtered solution in PBS (pH 7.4).
Stability And Storage	Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Anti-Siglec-6-Antibody, hFc Tag captured on CM5 Chip via Protein A can bind Human Siglec-6, His Tag with an affinity constant of 0.16 nM as determined in SPR assay (Biacore T200).
	Immobilized Human Siglec-6, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Anti-Siglec-6 Antibody, hFc Tag with the EC50 of 3.8ng/ml determined by ELISA (QC Test).
	Human Siglec-6 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.