Human Siglec-6/CD327 Protein (SIG-HM406)
Human Siglec-6/CD327 Protein (SIG-HM406)
Human Siglec-6/CD327 Protein (SIG-HM406)
  • Express System: HEK293
  • Product Tag: C-His-Avi
  • Purity: >95% as determined by Bis-Tris PAGE
  • Amino Acid Range: Gln27-Val331
Catalog #SIG-HM406
Regular price $315.00
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Product Description
Recombinant Human Siglec-6/CD327 Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Gln27-Val331.
Product Background
Siglecs (Sialic acid binding Ig-like Lectins) are I-type (Ig-type) lectins that belong to the Ig superfamily. They are characterized by an N-terminal Ig-like V-type domain which mediates sialic acid binding, followed by varying numbers of Ig-like C2-type domains. Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface.
Product Category
Recombinant Protein
Target
siglec-6
Synonyms
CD327; CD33 antigen-like 1; CD33L1; CDw327; OB-BP1; Siglec-6; SIGLEC6; CD33L; OBBP1
Accession
Species
Human
Biotinylated
no
Amino Acid Range
Gln27-Val331
Molecular Weight
The protein has a predicted MW of 36.6 kDa. Due to glycosylation, the protein migrates to 55-70 kDa based on Bis-Tris PAGE result.
Product Tag
C-His-Avi
Express System
HEK293
Purity
>95% as determined by Bis-Tris PAGE
Endotoxin
Less than 1 EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage
Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Human Siglec-6 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

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