Human SLAMF7/CRACC/CD319 Protein (SMF-HM207)
Human SLAMF7/CRACC/CD319 Protein (SMF-HM207)
  • Express System: HEK293
  • Product Tag: C-hFc
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Activity: Immobilized Human SLAMF7, hFc Tag at 0.5ug/ml (100ul/Well) on the plate. Dose response curve for Biotinylated Anti-SLAMF7 Antibody, hFc Tag with the EC50 10.4ng/ml determined by ELISA. See testing image for detail.
  • Amino Acid Range: Ser23-Met226
Catalog #SMF-HM207
Regular price $214.50
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Product Description

Recombinant Human SLAMF7/CRACC/CD319 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Ser23-Met226.

Product Background

CD2-like receptor activating cytotoxic cells (CRACC), also known as CS1, novel Ly9, SLAMF7, and CD319, is a 65-75 kDa type I transmembrane glycoprotein in the SLAM subgroup of the CD2 family.Self-ligand receptor of the signaling lymphocytic activation molecule (SLAM) family. SLAM receptors triggered by homo- or heterotypic cell-cell interactions are modulating the activation and differentiation of a wide variety of immune cells and thus are involved in the regulation and interconnection of both innate and adaptive immune response.

Product Category

Recombinant Protein / Antibody discovery / CAR-T targets
Protein
SLAMF7/CRACC/CD319
Synonyms
CD2 subset 1; CRACC; Novel Ly9; CD319; SLAMF7; CS1; 19A; FOAP-12
Accession
Species
Human
Biotinylated
no
Amino Acid Range
Ser23-Met226
Molecular Weight
The protein has a predicted MW of 49.2 kDa. Due to glycosylation, the protein migrates to 68-80 kDa based on Bis-Tris PAGE result.
Activity
Immobilized Human SLAMF7, hFc Tag at 0.5ug/ml (100ul/Well) on the plate. Dose response curve for Biotinylated Anti-SLAMF7 Antibody, hFc Tag with the EC50 10.4ng/ml determined by ELISA. See testing image for detail.

Product Tag

C-hFc
Expression System
HEK293
Purity
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin
Less than 1 EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage
-20 to -80°C for 12 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Immobilized Human SLAMF7, hFc Tag at 0.5ug/ml (100ul/Well) on the plate. Dose response curve for Biotinylated Anti-SLAMF7 Antibody, hFc Tag with the EC50 10.4ng/ml determined by ELISA. Immobilized Human SLAMF7, hFc Tag at 0.5ug/ml (100ul/Well) on the plate. Dose response curve for Biotinylated Anti-SLAMF7 Antibody, hFc Tag with the EC50 10.4ng/ml determined by ELISA.
Human SLAMF7 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Human SLAMF7 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Human SLAMF7 is greater than 95% as determined by SEC-HPLC. The purity of Human SLAMF7 is greater than 95% as determined by SEC-HPLC.
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