Product Description |
Recombinant Human ULBP-1 Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Gly26-Pro215. |
Product Background |
ULBP-1, or UL16-binding protein 1, is a protein that plays a significant role in the immune system, particularly in the recognition and elimination of abnormal cells, such as those found in cancer. It is a ligand for the NKG2D receptor, which is expressed on the surface of natural killer (NK) cells and certain T cells. The interaction between ULBP-1 and NKG2D can activate these immune cells, leading to the destruction of target cells. |
Product Category |
Recombinant Protein / Antibody discovery / Antibody discovery | Others |
Protein |
ULBP-1 |
Synonyms |
ALCAN-beta; NKG2D ligand 1; N2DL-1; NKG2DL1; MULT-1; NKG2DL; AET1I; ULBP1; ULBP-1;ALCAN-β |
Accession |
|
Species |
Human |
Biotinylated |
no |
Amino Acid Range |
Gly26-Pro215 |
Molecular Weight |
The protein has a predicted MW of 25.2 kDa. Due to glycosylation, the protein migrates to 28-35 kDa based on Bis-Tris PAGE result. |
Activity |
Immobilized Human ULBP-1, His Tag at 5 ug/ml (100 ul/well) on the plate. Dose response curve for Human NKG2D, hFc Tag with the EC50 of 0.22 ug/ml determined by ELISA. See testing image for detail. |
Product Tag |
C-His-Avi |
Expression System |
HEK293 |
Purity |
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
Endotoxin |
Less than 1 EU per ug by the LAL method. |
Form |
Lyophilized |
Shipping |
Shipped at ambient temperature. |
Formulation |
Lyophilized from 0.22 um filtered solution in 20 mM PB, 0.5 M NaCl, 0.1 M L-arginine (pH 8.0). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution |
Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking. |
Stability And Storage |
-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
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Immobilized Human ULBP-1, His Tag at 5 ug/ml (100 ul/well) on the plate. Dose response curve for Human NKG2D, hFc Tag with the EC50 of 0.22 ug/ml determined by ELISA. |
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Human ULBP-1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. |
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The purity of Human ULBP-1 is greater than 95% as determined by SEC-HPLC. |
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