Mouse BCMA/TNFRSF17 Protein (BCM-MM217)
Mouse BCMA/TNFRSF17 Protein (BCM-MM217)
  • Express System: HEK293
  • Product Tag: C-hFc
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Activity: Immobilized Mouse APRIL, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Mouse BCMA, hFc Tag with the EC50 of 2.2ng/ml determined by ELISA (QC Test). The affinity constant of 6.59 nM as determined in SPR assay (Biacore T200). See testing image for detail.
  • Amino Acid Range: Met1-Thr49
Catalog #BCM-MM217
Regular price $297.00
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Product Description

Recombinant Mouse BCMA/TNFRSF17 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Met1-Thr49.

Product Background

B-cell maturation antigen (BCMA or BCM), also known as tumor necrosis factor receptor superfamily member 17 (TNFRSF17), is a protein that in humans is encoded by the TNFRSF17 gene.TNFRSF17 is a cell surface receptor of the TNF receptor superfamily which recognizes B-cell activating factor (BAFF).

Product Category

Recombinant Protein / Antibody discovery / CAR-T targets
Protein
BCMA/TNFRSF17
Synonyms
CD269; TNFRSF17; BCMA; BCM; TNFRSF13A
Accession
Species
Mouse
Biotinylated
no
Amino Acid Range
Met1-Thr49
Molecular Weight
The protein has a predicted MW of 31 kDa. Due to glycosylation, the protein migrates to 38-45 kDa based on Bis-Tris PAGE result.
Activity
Immobilized Mouse APRIL, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Mouse BCMA, hFc Tag with the EC50 of 2.2ng/ml determined by ELISA (QC Test). The affinity constant of 6.59 nM as determined in SPR assay (Biacore T200). See testing image for detail.

Product Tag

C-hFc
Expression System
HEK293
Purity
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin
Less than 1 EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage
-20 to -80°C for 12 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Human BAFF Trimer, His Tag captured on CM5 Chip via Anti-His Antibody can bind Mouse BCMA, hFc Tag with an affinity constant of 6.59 nM as determined in SPR assay (Biacore T200). Human BAFF Trimer, His Tag captured on CM5 Chip via Anti-His Antibody can bind Mouse BCMA, hFc Tag with an affinity constant of 6.59 nM as determined in SPR assay (Biacore T200).
Immobilized Mouse APRIL, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Mouse BCMA, hFc Tag with the EC50 of 2.2ng/ml determined by ELISA (QC Test). Immobilized Mouse APRIL, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Mouse BCMA, hFc Tag with the EC50 of 2.2ng/ml determined by ELISA (QC Test).
Immobilized Mouse BAFF, mFc Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Mouse BCMA, hFc Tag with the EC50 of 0.19ug/ml determined by ELISA. Immobilized Mouse BAFF, mFc Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Mouse BCMA, hFc Tag with the EC50 of 0.19ug/ml determined by ELISA.
Mouse BCMA on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Mouse BCMA on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Mouse BCMA is greater than 95% as determined by SEC-HPLC. The purity of Mouse BCMA is greater than 95% as determined by SEC-HPLC.
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