Mouse c-MPL/Thrombopoietin R Protein (MPL-MM101)
Mouse c-MPL/Thrombopoietin R Protein (MPL-MM101)
  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Amino Acid Range: Gln26-Trp482
  • Recommended Products:
Catalog #MPL-MM101
Regular price $363.00
/
Size

Order by 4pm ET for delivery on:

Mouse c-MPL/Thrombopoietin R Protein (MPL-MM101) Summary

Product Description

Recombinant Mouse c-MPL/Thrombopoietin R Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Gln26-Trp482.

Product Background

The c-mpl gene encodes a member of the hematopoietic cytokine receptor superfamily. This gene was discovered through the study of a murine retrovirus which induces an acute myeloproliferative syndrome in mice.MPLV (for myeloproliferative leukemia virus) has transduced a truncated and constitutively activated form of the c-mpl receptor chain. High levels of c-mpl expression were detected in 45% of acute myeloid leukemia (AML). No correlation was found between c-mpl expression and the French-American-British classification subtype of AML.

Product Category

Recombinant Protein / Antibody discovery / Antibody discovery | Others

Mouse c-MPL/Thrombopoietin R Protein (MPL-MM101) Specifications/Details

Protein
c-MPL/Thrombopoietin R
Synonyms
TPO-R; CD110; MPL; c-Mpl; MPLV; K12
Accession
Species
Mouse
Biotinylated
no
Amino Acid Range
Gln26-Trp482
Molecular Weight
The protein has a predicted MW of 52.3 kDa. Due to glycosylation, the protein migrates to 65-70 kDa based on Bis-Tris PAGE result.
Product Tag
C-His
Expression System
HEK293
Purity
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin
Less than 1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage
-20 to -80°C for 12 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

Mouse c-MPL on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Mouse c-MPL on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Mouse c-MPL is greater than 95% as determined by SEC-HPLC. The purity of Mouse c-MPL is greater than 95% as determined by SEC-HPLC.
Have more questions?

Check out our Frequently Asked Questions page for more details about product specifications, ordering, and shipments.

Recently viewed