Name: Mouse Fc gamma RIV/CD16-2 Protein (FCR-MM162)
Brand: KactusBio
SKU: FCR-MM162-100UG
Price: 346.5 USD
Availability: InStock

Mouse Fc gamma RIV/CD16-2 Protein (FCR-MM162)

Mouse Fc gamma RIV, His Tag captured on CM5 Chip via anti-his antibody can bind Anti-CD3 Antibody with an affinity constant of 146 nM as determined in SPR assay (Biacore T200).

Mouse Fc gamma RIV on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

Loaded Mouse Fc gamma RIV, His Tag on Anti-His-Biosensor, can bind Anti-CD3 Antibody(OKT3) with an affinity constant of 0.21 µM as determined in BLI assay (Gator).

The purity of Mouse Fc gamma RIV is greater than 95% as determined by SEC-HPLC.

Express System: HEK293
Product Tag: C-His
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: The affinity constant of 146 nM as determined in SPR assay (Biacore T200). See testing image for detail.
Amino Acid Range: Gly21-Gln203

Catalog #FCR-MM162

Size

100UG

500UG

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Product Description	Recombinant Mouse Fc gamma RIV/CD16-2 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Gly21-Gln203.
Product Background	FcgammaRIV is a relatively new IgG Fc receptor (FcgammaR) that is reported to contribute to the pathogenesis of autoimmune diseases.FcgammaRIII and FcgammaRIV are each essential to trigger an FcRgamma-linker for activation of T-cell-dependent signal that drives C5a production in the Arthus reaction. A combined requirement for FcgammaRIII and FcgammaRIV in autoimmune injury, and identify the linker for activation of T cells adaptor as an integral component of linked FcgammaR and C5a anaphylatoxin receptor activation to generate inflammation.
Product Category	Recombinant Protein / Antibody discovery / Fc receptors

Protein	Fc gamma RIV/CD16-2
Synonyms	CD16-2; FcgammaRIV; Fcgr4; FcγRIV
Accession	A0A0B4J1G0-1
Species	Mouse
Biotinylated	no
Amino Acid Range	Gly21-Gln203
Molecular Weight	The protein has a predicted MW of 22 kDa. Due to glycosylation, the protein migrates to 32-43 kDa based on Bis-Tris PAGE result.
Activity	The affinity constant of 146 nM as determined in SPR assay (Biacore T200). See testing image for detail.
Product Tag	C-His
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1 EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Mouse Fc gamma RIV, His Tag captured on CM5 Chip via anti-his antibody can bind Anti-CD3 Antibody with an affinity constant of 146 nM as determined in SPR assay (Biacore T200).
	Mouse Fc gamma RIV on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	Loaded Mouse Fc gamma RIV, His Tag on Anti-His-Biosensor, can bind Anti-CD3 Antibody(OKT3) with an affinity constant of 0.21 µM as determined in BLI assay (Gator).
	The purity of Mouse Fc gamma RIV is greater than 95% as determined by SEC-HPLC.

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