Name: Mouse Hepcidin/HAMP Protein (HEP-ME601)
Brand: KactusBio
SKU: HEP-ME601-100UG
Price: 330.0 USD
Availability: InStock

Catalog #HEP-ME601

Size

100UG

500UG

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Product Description	Recombinant Mouse Hepcidin/HAMP Protein is expressed from E.coli with GST tag at the N-Terminus.It contains Asp59-Thr83.
Product Background	Hepcidin, the main regulator of iron metabolism, is synthesized and released by hepatocytes in response to increased body iron concentration and inflammation. Deregulation of hepcidin expression is a common feature of genetic and acquired iron disorders: in Hereditary Hemochromatosis (HH) and iron-loading anemias low hepcidin causes iron overload, while in Iron Refractory Iron Deficiency Anemia (IRIDA) and anemia of inflammation (AI), high hepcidin levels induce iron-restricted erythropoiesis.
Product Category	Recombinant Protein / Antibody discovery / Antibody discovery \| Others

Protein	Hepcidin/HAMP
Synonyms	Hamp1; Hepc; Hepc1; HFE2B; LEAP1; LEAP-1; PLTR
Accession	Q9EQ21
Species	Mouse
Biotinylated	no
Amino Acid Range	Asp59-Thr83
Molecular Weight	The protein has a predicted MW of 29.05 kDa same as Bis-Tris PAGE result.
Product Tag	N-GST
Expression System	E.coli
Purity	> 95% as determined by Bis-Tris PAGE
Endotoxin	Less than 1 EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in 50mM Tris-HCl, 150mM NaCl, 2mM DTT (pH 7.5). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.