Name: Mouse Integrin alpha V beta 3 (ITGAV&ITGB3) Heterodimer Protein (ITG-MM1V3)
Brand: KactusBio
SKU: ITG-MM1V3-100UG
Price: 412.5 USD
Availability: InStock

SEC-HPLC chromatogram of purified recombinant protein showing a single major peak at approximately 6.8 minutes retention time, indicating protein quality analysis.

Mouse Integrin alpha V beta 3 (ITGAV&ITGB3) Heterodimer Protein (ITG-MM1V3)

Mouse ITGAV&ITGB3 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

The purity of Mouse ITGAV&ITGB3 is greater than 95% as determined by SEC-HPLC.

Express System: HEK293
Product Tag: C-His
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Amino Acid Range: Phe31-Val988(ITGAV) acidic tail & Glu26-Asp717(ITGB3) basic tail

Catalog #ITG-MM1V3

Size

100UG

500UG

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Mouse Integrin alpha V beta 3 (ITGAV&ITGB3) Heterodimer Protein (ITG-MM1V3) Summary

Product Description	Recombinant Mouse Integrin alpha V beta 3 (ITGAV&ITGB3) Heterodimer Protein is expressed from HEK293 with His tag at the C-Terminus of ITGAV.It contains Phe31-Val988 (ITGAV) acidic tail and Glu26-Asp717 (ITGB3) basic tail.
Product Background	ITGAV&ITGB3 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling. ITGAV&ITGB3 binds to FGF1 and this binding is essential for FGF1 signaling. ITGAV&ITGB3 binds to FGF2 and this binding is essential for FGF2 signaling. ITGAV&ITGB3 binds to IGF1 and this binding is essential for IGF1 signaling. ITGAV&ITGB3 binds to IGF2 and this binding is essential for IGF2 signaling.
Product Category	Recombinant Protein / Antibody discovery / Antibody discovery \| Others

Mouse Integrin alpha V beta 3 (ITGAV&ITGB3) Heterodimer Protein (ITG-MM1V3) Specifications/Details

Protein	Integrin alpha V beta 3 (ITGAV&ITGB3) Heterodimer
Synonyms	αVβ3; Integrin alpha V beta 3; beta3; alphaV; ITGAV&ITGB3; Integrin alpha V β 3; β3
Accession	P43406(ITGAV)&O54890(ITGB3)
Species	Mouse
Biotinylated	no
Amino Acid Range	Phe31-Val988(ITGAV) acidic tail & Glu26-Asp717(ITGB3) basic tail
Molecular Weight	The protein has a predicted MW of 131.48 kDa (ITGAV) and 80.80 kDa (ITGB3). Due to enzyme lysis and glycosylation, the protein migrates to 90-130 kDa based on Bis-Tris PAGE result.
Product Tag	C-His
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

	Mouse ITGAV&ITGB3 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Mouse ITGAV&ITGB3 is greater than 95% as determined by SEC-HPLC.