Mouse Integrin alpha V beta 3 (ITGAV&ITGB3) Heterodimer Protein (ITG-MM1V3)

  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
  • Exact Sequence: Phe31-Val988(ITGAV)acidic tail & Glu26-Asp717(ITGB3)basic tail

Catalog: ITG-MM1V3

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Product Description Recombinant Mouse Integrin alpha V beta 3 (ITGAV&ITGB3) Heterodimer Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Phe31-Val988(ITGAV) acidic tail&Glu26-Asp717(ITGB3) basic tail.

Product Background

ITGAV&ITGB3 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling. ITGAV&ITGB3 binds to FGF1 and this binding is essential for FGF1 signaling. ITGAV&ITGB3 binds to FGF2 and this binding is essential for FGF2 signaling. ITGAV&ITGB3 binds to IGF1 and this binding is essential for IGF1 signaling. ITGAV&ITGB3 binds to IGF2 and this binding is essential for IGF2 signaling.

Product Category

Recombinant Protein

Target

Integrin alpha V beta 3 (ITGAV&ITGB3) Heterodimer

Gene/Protein ID

P43406(ITGAV)&O54890(ITGB3)

Species

Mouse

Exact Sequence

Phe31-Val988(ITGAV)acidic tail & Glu26-Asp717(ITGB3)basic tail
Molecular Weight The protein has a predicted MW of 131.48 kDa(ITGAV)&80.80 kDa(ITGB3). Due to enzyme lysis and glycosylation, the protein migrates to 90-130 kDa based on Tris-Bis PAGE result.

Product Tag

C-His

Express System

HEK293
Purity > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin Less than 1EU per ug by the LAL method.
Form Lyophilized
Shipping Shipped at ambient temperature.
Formulation Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
The purity of Mouse ITGAV&ITGB3 is greater than 95% as determined by SEC-HPLC.
Mouse ITGAV&ITGB3 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

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