Product Description |
Recombinant Mouse TNFRSF12A/TWEAKR Protein is expressed from HEK293 with hFc tag at the N-Terminus.It contains Glu28-Per80. |
Product Background |
Thyroid cancer (TC) is the most well-known endocrine neoplasia as well as a common malignant tumor in the head and neck.TNFRSF12A expression may be a potential useful prognostic molecular biomarker of bad survival in thyroid cancer, in addition, PPAR signaling pathway, insulin signaling pathway, mTOR signaling pathway may be the key pathway controlled by TNFRSF12A in thyroid cancer. Further experimental ought to be performed to demonstrate the biologic effect of TNFRSF12A. |
Product Category |
Recombinant Protein |
Target |
TNFRSF12A/TWEAKR |
Synonyms |
FGF-inducible 14; Fgfrp2; TNFRSF12A; FN14; CD266; TWEAKR |
Accession |
|
Species |
Mouse |
Biotinylated |
no |
Amino Acid Range |
Glu28-Per80 |
Molecular Weight |
The protein has a predicted MW of 32.8 kDa. Due to glycosylation, the protein migrates to 40-50 kDa based on Bis-Tris PAGE result. |
Activity |
Immobilized Mouse TNFRSF12A, hFc Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Mouse TNFSF12, Rabbit Fc Tag with the EC50 of 0.12ug/ml determined by ELISA (QC Test). The affinity constant of 0.15 nM as determined in SPR assay (Biacore T200). See testing image for detail. |
Product Tag |
N-hFc |
Express System |
HEK293 |
Purity |
>95% as determined by Bis-Tris PAGE;>95% as determined by HPLC |
Endotoxin |
Less than 1EU per ug by the LAL method. |
Form |
Lyophilized |
Shipping |
Shipped at ambient temperature. |
Formulation |
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution |
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
Stability And Storage |
Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
|
|
Human TNFSF12, hFc Tag immobilized on CM5 Chip can bind Mouse TNFRSF12A, hFc Tag with an affinity constant of 0.15 nM as determined in SPR assay (Biacore T200). |
|
|
Immobilized Mouse TNFRSF12A, hFc Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Mouse TNFSF12, Rabbit Fc Tag with the EC50 of 0.12ug/ml determined by ELISA (QC Test). |
|
|
Mouse TNFRSF12A on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. |
|
|
The purity of Mouse TNFRSF12A is greater than 95% as determined by SEC-HPLC. |
Related Products
Have more questions?
Check out our Frequently Asked Questions page for more details about product specifications, ordering, and shipments.
Contact Us
Recently viewed
