Biotinylated Human HLA-A*02:01&B2M&AFP (PLFQVPEPV) Monomer Protein (MHC-HM408B)

  • Express System: HEK293
  • Product Tag: C-His-Avi
  • Purity: > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
  • Biotinylated: yes
  • Amino Acid Range: Gly25-Thr305(HLA-A*02:01),Ile21-Met119(B2M)and PLFQVPEPV peptide

Catalog: MHC-HM408B


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Product Description Recombinant Biotinylated Human HLA-A*02:01&B2M&AFP (PLFQVPEPV) Monomer Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Gly25-Thr305(HLA-A*02:01),Ile21-Met119(B2M) and PLFQVPEPV peptide.

Product Background

Alpha-fetoprotein (AFP), a specific liver cancer marker, T cells expressing AFP-CAR selectively degranulated, released cytokines, and lysed liver cancer cells that were HLA-A*02:01 /AFP while sparing cells from multiple tissue types that were negative for either expressed proteins.CAR T-cell immunotherapy targeting intracellular/secreted solid tumor antigens can elicit a potent antitumor response.

Product Category

Recombinant Protein


HLA-A*02:01&B2M&AFP (PLFQVPEPV) Monomer
MHC Form Monomer
Allele HLA-A*02:01



Amino Acid Range

Gly25-Thr305(HLA-A*02:01),Ile21-Met119(B2M)and PLFQVPEPV peptide
Molecular Weight The protein has a predicted MW of 50.4 kDa. Due to glycosylation, the protein migrates to 53-63 kDa based on Tris-Bis PAGE result.

Product Tag


Express System

Purity > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin Less than 1EU per ug by the LAL method.
Form Lyophilized
Shipping Shipped at ambient temperature.
Formulation Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
The purity of Biotinylated Human HLA-A*02:01&B2M&AFP (PLFQVPEPV) Monomer is greater than 95% as determined by SEC-HPLC.
Biotinylated Human HLA-A*02:01&B2M&AFP (PLFQVPEPV) Monomer on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

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