Name: Biotinylated Human IL-1 Rrp2/IL-1 R6 Protein (IL1-HM4L2B)
Brand: KactusBio
SKU: IL1-HM4L2B-100UG
Price: 577.5 USD
Availability: InStock

Biotinylated Human IL-1 Rrp2/IL-1 R6 Protein (IL1-HM4L2B)

Immobilized Biotinylated Human IL-1 Rrp2, His Tag at 0.5ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Spesolimab, hFc Tag with the EC50 of 3.3ng/ml determined by ELISA.

Biotinylated Human IL-1 Rrp2 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

The purity of Biotinylated Human IL-1 Rrp2 is greater than 90% as determined by SEC-HPLC.

Express System: HEK293
Product Tag: C-His-Avi
Purity: > 95% as determined by Bis-Tris PAGE;> 90% as determined by HPLC
Activity: Immobilized Biotinylated Human IL-1 Rrp2, His Tag at 0.5ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Spesolimab, hFc Tag with the EC50 of 3.3ng/ml determined by ELISA. See testing image for detail.
Amino Acid Range: Asp20-Arg335

Catalog #IL1-HM4L2B

Size

100UG

500UG

Order now, ships by:

[{"id":42618365182174,"title":"100UG","option1":"100UG","option2":null,"option3":null,"sku":"IL1-HM4L2B-100UG","requires_shipping":true,"taxable":true,"featured_image":null,"available":true,"name":"Biotinylated Human IL-1 Rrp2\/IL-1 R6 Protein (IL1-HM4L2B) - 100UG","public_title":"100UG","options":["100UG"],"price":57750,"weight":5,"compare_at_price":null,"inventory_management":"shopify","barcode":null,"requires_selling_plan":false,"selling_plan_allocations":[],"quantity_rule":{"min":1,"max":null,"increment":1}},{"id":43584305463518,"title":"500UG","option1":"500UG","option2":null,"option3":null,"sku":"IL1-HM4L2B-500UG","requires_shipping":true,"taxable":true,"featured_image":null,"available":true,"name":"Biotinylated Human IL-1 Rrp2\/IL-1 R6 Protein (IL1-HM4L2B) - 500UG","public_title":"500UG","options":["500UG"],"price":192500,"weight":5,"compare_at_price":null,"inventory_management":"shopify","barcode":null,"requires_selling_plan":false,"selling_plan_allocations":[],"quantity_rule":{"min":1,"max":null,"increment":1}}]

Biotinylated Human IL-1 Rrp2/IL-1 R6 Protein (IL1-HM4L2B) Summary

Product Description	Recombinant Biotinylated Human IL-1 Rrp2/IL-1 R6 Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Asp20-Arg335.
Product Background	The Interleukin 1 receptor family (IL-1 R) comprises at least eleven members including IL-1 RI (IL-1 R1), IL-1 RII (IL-1 R2), IL-1 RAcP (IL‑1 R3), ST2 (T1/IL-1 R4), IL-18 Ra (IL-1 Rrp/IL-1 R5), IL-1 Rrp2 (IL-1 RL2/IL-1 R6), IL-18 Rb (AcPL/IL-1 R7), IL-1RAPL‑1 (TIGIRR‑2/IL‑1 R8), and TIGIRR-1 (IL-1 R9). IL1RL2 is a receptor for interleukin-36 (IL36A, IL36B and IL36G). After binding to interleukin-36 associates with the coreceptor IL1RAP to form the interleukin-36 receptor complex which mediates interleukin-36-dependent activation of NF-kappa-B, MAPK and other pathways.
Product Category	Recombinant Protein / Antibody discovery / Antibody discovery \| Others

Biotinylated Human IL-1 Rrp2/IL-1 R6 Protein (IL1-HM4L2B) Specifications/Details

Protein	IL-1 Rrp2/IL-1 R6
Synonyms	IL-1 R6; IL-1 Rrp2; IL1RL2; IL1Rrp2; IL1RRP2; IL-36R
Accession	Q9HB29-1
Species	Human
Biotinylated	yes
Amino Acid Range	Asp20-Arg335
Molecular Weight	The protein has a predicted MW of 39.1 kDa. Due to glycosylation, the protein migrates to 55-75 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Biotinylated Human IL-1 Rrp2, His Tag at 0.5ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Spesolimab, hFc Tag with the EC50 of 3.3ng/ml determined by ELISA. See testing image for detail.
Product Tag	C-His-Avi
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 90% as determined by HPLC
Endotoxin	Less than 1 EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Biotinylated Human IL-1 Rrp2, His Tag at 0.5ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Spesolimab, hFc Tag with the EC50 of 3.3ng/ml determined by ELISA.
	Biotinylated Human IL-1 Rrp2 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Biotinylated Human IL-1 Rrp2 is greater than 90% as determined by SEC-HPLC.