Name: Biotinylated Human Integrin alpha V beta 5 (ITGAV&ITGB5) Heterodimer Protein (ITG-HM4V5B)
Brand: KactusBio
SKU: ITG-HM4V5B-100UG
Price: 600.0 USD
Availability: InStock

Biotinylated Human Integrin alpha V beta 5 (ITGAV&ITGB5) Heterodimer Protein (ITG-HM4V5B)

Immobilized Biotinylated Human ITGAV&ITGB5, His Tag at 1ug/ml (100ul/Well) on streptavidin (5ug/ml) precoated plate. Dose response curve for Anti-alpha V Antibody, hFc Tag with the EC50 of 9.6ng/ml determined by ELISA (QC Test).

Biotinylated Human ITGAV&ITGB5 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

The purity of Biotinylated Human ITGAV&ITGB5 is greater than 95% as determined by SEC-HPLC.

Express System: HEK293
Product Tag: C-His-Avi
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: Immobilized Biotinylated Human ITGAV&ITGB5, His Tag at 1ug/ml (100ul/Well) on streptavidin (5ug/ml) precoated plate. Dose response curve for Anti-alpha V Antibody, hFc Tag with the EC50 of 9.6ng/ml determined by ELISA (QC Test). See testing image for detail.
Amino Acid Range: Phe31-Val992(ITGAV) acidic tail & Gly24-Asn719(ITGB5) basic tail

Catalog #ITG-HM4V5B

Size

100UG

500UG

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Product Description	Recombinant Biotinylated Human Integrin alpha V beta 5 (ITGAV&ITGB5) Heterodimer Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Phe31-Val992(ITGAV) acidic tail & Gly24-Asn719(ITGB5) basic tail.
Product Background	Integrin ITGAV & ITGB5 is a type of integrin that binds to matrix macromolecules and proteinases and thereby stimulates angiogenesis. However, it inhibits angiogenesis. It consists of two components, integrin alpha V and integrin beta 5. Integrin ITGAV & ITGB5 is a receptor for fibronectin. It recognizes the sequence R-G-D in its ligand.(Microbial infection)- Integrin ITGAV & ITGB5 acts as a receptor for adenovirus type C.
Product Category	Recombinant Protein / Antibody discovery

Protein	Integrin alpha V beta 5 (ITGAV&ITGB5) Heterodimer
Synonyms	αVβ5; Integrin alpha V beta 5; beta5; alphaV; ITGAV&ITGB5;Integrin alpha V β 5; β5
Accession	P06756-1(ITGAV)&P18084(ITGB5)
Species	Human
Biotinylated	yes
Amino Acid Range	Phe31-Val992(ITGAV) acidic tail & Gly24-Asn719(ITGB5) basic tail
Molecular Weight	The protein has a predicted MW of 114 kDa (ITGAV) & 81.4 kDa (ITGB5). Due to glycosylation, the protein migrates to 85-140 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Biotinylated Human ITGAV&ITGB5, His Tag at 1ug/ml (100ul/Well) on streptavidin (5ug/ml) precoated plate. Dose response curve for Anti-alpha V Antibody, hFc Tag with the EC50 of 9.6ng/ml determined by ELISA (QC Test). See testing image for detail.
Product Tag	C-His-Avi
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Biotinylated Human ITGAV&ITGB5, His Tag at 1ug/ml (100ul/Well) on streptavidin (5ug/ml) precoated plate. Dose response curve for Anti-alpha V Antibody, hFc Tag with the EC50 of 9.6ng/ml determined by ELISA (QC Test).
	Biotinylated Human ITGAV&ITGB5 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Biotinylated Human ITGAV&ITGB5 is greater than 95% as determined by SEC-HPLC.