Product Description |
Recombinant Biotinylated Mouse Siglec-15/CD33L3 Protein (Primary Amine Labeling) is expressed from HEK293 with His tag at the C-Terminus.It contains Arg24-Thr262. |
Product Background |
Siglec-15 is a transmembrane glycoprotein in the Siglec family of sialic acid-binding immune regulatory molecules. Mature human Siglec-15 consists of a 244 amino acid extracellular domain (ECD) with two Ig-like domains, a 21 aa transmembrane segment, and a 44 aa cytoplasmic domain. Siglec-15 is a potential therapeutic target for osteoporosis and plays a conserved regulatory role in the immune system of vertebrates. |
Product Category |
Recombinant Protein |
Target |
Siglec-15/CD33L3 |
Synonyms |
CD33 molecule-like 3; CD33L3; HsT1361; Siglec15; CD33 antigen-like 3; SIGLEC-15 |
Accession |
|
Species |
Mouse |
Biotinylated |
yes |
Amino Acid Range |
Arg24-Thr262 |
Molecular Weight |
The protein has a predicted MW of 26.7 kDa. Due to glycosylation, the protein migrates to 35-43 kDa based on Bis-Tris PAGE result. |
Product Tag |
C-His |
Express System |
HEK293 |
Purity |
> 95% as determined by Bis-Tris PAGE |
Endotoxin |
Less than 1EU per ug by the LAL method. |
Form |
Liquid |
Shipping |
Shipped with dry ice. |
Formulation |
Supplied as 0.22um filtered solution in 20mM PB, 0.5M NaCl, 0.1M L-arginine (pH 7.4). |
Stability And Storage |
Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
|
|
Biotinylated Mouse Siglec-15/CD33L3 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. |
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