Name: Cynomolgus c-MPL/Thrombopoietin R Protein (MPL-CM101)
Brand: KactusBio
SKU: MPL-CM101-100UG
Price: 346.5 USD
Availability: InStock

Cynomolgus c-MPL/Thrombopoietin R Protein (MPL-CM101)

Immobilized Cynomolgus c-MPL, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-C-MPL Antibody, hFc Tag with the EC50 of 3.0ng/ml determined by ELISA (QC Test).

Cynomolgus c-MPL on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

Express System: HEK293
Product Tag: C-His
Purity: > 95% as determined by Bis-Tris PAGE
Activity: Immobilized Cynomolgus c-MPL, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-C-MPL Antibody, hFc Tag with the EC50 of 3.0ng/ml determined by ELISA (QC Test). See testing image for detail.
Amino Acid Range: Gln22-Thr489

Catalog #MPL-CM101

Size

100UG

500UG

Order by 4pm ET for delivery on:

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Cynomolgus c-MPL/Thrombopoietin R Protein (MPL-CM101) Summary

Product Description	Recombinant Cynomolgus c-MPL/Thrombopoietin R Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Gln22-Thr489.
Product Background	The c-mpl gene encodes a member of the hematopoietic cytokine receptor superfamily. This gene was discovered through the study of a murine retrovirus which induces an acute myeloproliferative syndrome in mice.MPLV (for myeloproliferative leukemia virus) has transduced a truncated and constitutively activated form of the c-mpl receptor chain. High levels of c-mpl expression were detected in 45% of acute myeloid leukemia (AML). No correlation was found between c-mpl expression and the French-American-British classification subtype of AML.
Product Category	Recombinant Protein / Antibody discovery / Antibody discovery \| Others

Cynomolgus c-MPL/Thrombopoietin R Protein (MPL-CM101) Specifications/Details

Protein	c-MPL/Thrombopoietin R
Synonyms	TPO-R; CD110; MPL; c-Mpl; MPLV; K12
Accession	A0A2K5UGC7
Species	Cynomolgus
Biotinylated	no
Amino Acid Range	Gln22-Thr489
Molecular Weight	The protein has a predicted MW of 53.48 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Cynomolgus c-MPL, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-C-MPL Antibody, hFc Tag with the EC50 of 3.0ng/ml determined by ELISA (QC Test). See testing image for detail.
Product Tag	C-His
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE
Endotoxin	Less than 1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form	Liquid
Shipping	Shipped with dry ice.
Formulation	Supplied as 0.22um filtered solution in 20mM Tris, 500mM NaCl, 3mM DTT, 10% Glycerol (pH 7.5).
Stability And Storage	Valid for 12 months from date of receipt when stored at -80°C.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

	Immobilized Cynomolgus c-MPL, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-C-MPL Antibody, hFc Tag with the EC50 of 3.0ng/ml determined by ELISA (QC Test).
	Cynomolgus c-MPL on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.