Name: Cynomolgus MMP-8 Protein (MMP-CM108)
Brand: KactusBio
SKU: MMP-CM108-100UG
Price: 315.0 USD
Availability: InStock

Express System: HEK293
Product Tag: C-His
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: Immobilized Cynomolgus MMP-8, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Anti-MMP-8 Antibody, hFc Tag with the EC50 of 20.2ng/ml determined by ELISA (QC tested). See testing image for detail.
Amino Acid Range: Phe21-Ser467

Catalog #MMP-CM108

Size

100UG

500UG

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Product Description	Recombinant Cynomolgus MMP-8 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Phe21-Ser467.
Product Background	Alteration of matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs) expression has been studied for various cardiac diseases, including dilated cardiomyopathy (DCM), with the significance of surrogate markers of extracellular matrix (ECM) remodeling. MMP-8 was identified only in myocardiocytes, while MMP-9 and TIMP-2 were present in both myocardiocytes and stroma, but with different intensity. The increasing intensity of MMP-8 and TIMP-2 immunoreactions was significantly associated with low HCS.
Product Category	Recombinant Protein / Antibody discovery

Protein	MMP-8
Synonyms	PMNL-CL; CLG1; MMP8; Collagenase 2; PMNL-CL; HNC
Accession	XP_005579523.2
Species	Cynomolgus
Biotinylated	no
Amino Acid Range	Phe21-Ser467
Molecular Weight	The protein has a predicted MW of 52.27 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Cynomolgus MMP-8, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Anti-MMP-8 Antibody, hFc Tag with the EC50 of 20.2ng/ml determined by ELISA (QC tested). See testing image for detail.
Product Tag	C-His
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Cynomolgus MMP-8, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Anti-MMP-8 Antibody, hFc Tag with the EC50 of 20.2ng/ml determined by ELISA (QC tested).
	Cynomolgus MMP-8 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Cynomolgus MMP-8 is greater than 95% as determined by SEC-HPLC.