Name: Cynomolgus Nectin-4 Protein (NEC-CM104)
Brand: KactusBio
SKU: NEC-CM104-100UG
Price: 346.5 USD
Availability: InStock

Express System: HEK293
Product Tag: C-His
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: Immobilized Cynomolgus Nectin-4, His Tag at 1ug/ml (100ul/Well) on the plate. Dose response curve for Anti-Nectin-4 Antibody, hFc Tag with the EC50 of 3.4ng/ml determined by ELISA. See testing image for detail.
Amino Acid Range: Gly32-Val351

Catalog #NEC-CM104

Size

100UG

500UG

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Cynomolgus Nectin-4 Protein (NEC-CM104) Summary

Product Description	Recombinant Cynomolgus Nectin-4 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Gly32-Val351.
Product Background	NECTIN-4 [a poliovirus receptor-related-4 (pvrl-4) encoded protein] is a Ca2+ independent immunoglobulin-like protein. Along with other Nectins (Nectin-1, -2 and -3), it is primarily involved in cell-cell adhesion. In contrast to other Nectins, Nectin-4 is specifically enriched in the embryonic and placental tissues but its expression significantly declines in adult life.
Product Category	Recombinant Protein / Antibody discovery / CAR-T targets

Cynomolgus Nectin-4 Protein (NEC-CM104) Specifications/Details

Protein	Nectin-4
Synonyms	EDSS1; LNIR; Nectin4; PRR4; NECTIN4; PVRL4
Accession	XP_005541277.1
Species	Cynomolgus
Biotinylated	no
Amino Acid Range	Gly32-Val351
Molecular Weight	The protein has a predicted MW of 35.9 kDa. Due to glycosylation, the protein migrates to 38-48 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Cynomolgus Nectin-4, His Tag at 1ug/ml (100ul/Well) on the plate. Dose response curve for Anti-Nectin-4 Antibody, hFc Tag with the EC50 of 3.4ng/ml determined by ELISA. See testing image for detail.
Product Tag	C-His
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1 EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Cynomolgus Nectin-4, His Tag at 1ug/ml (100ul/Well) on the plate. Dose response curve for Anti-Nectin-4 Antibody, hFc Tag with the EC50 of 3.4ng/ml determined by ELISA.
	Cynomolgus Nectin-4 on Bis-Tris PAGE under reduced conditions. The purity is greater than 95%.
	The purity of Cynomolgus Nectin-4 is greater than 95% as determined by SEC-HPLC.