Cynomolgus PRLR Protein (PLR-CM101)

Express System: HEK293
Product Tag: C-His
Purity: > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Activity: Immobilized Cynomolgus PRLR, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Anti-PRLR Antibody, hFc Tag with the EC50 of 34.6ng/ml determined by ELISA. See testing image for detail.
Exact Sequence: Gln25-Thr236

Catalog: PLR-CM101

Order now get it on

Bulk Quote | Test Sample

Product Description	Recombinant Cynomolgus PRLR Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Gln25-Thr236.
Product Background	Prolactin receptor (PRLR) is highly expressed in a subset of human breast cancer and prostate cancer, which makes it a potential target for cancer treatment. In clinical trials, the blockade of PRLR was shown to be safe but with poor efficacy. It is therefore urgent to develop new therapies against PRLR target. Bispecific antibodies (BsAbs) could guide immune cells toward tumor cells, and produced remarkable effects in some cancers.
Product Category	Recombinant Protein

Target	PRLR
Gene/Protein ID	A0A2K5WXK1
Species	Cynomolgus
Exact Sequence	Gln25-Thr236
Molecular Weight	The protein has a predicted MW of 25.75 kDa. Due to glycosylation, the protein migrates to 35-50 kDa based on Tris-Bis PAGE result.
Activity	Immobilized Cynomolgus PRLR, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Anti-PRLR Antibody, hFc Tag with the EC50 of 34.6ng/ml determined by ELISA. See testing image for detail.
Product Tag	C-His
Express System	HEK293
Purity	> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in 50mM Tris, 150mM NaCl (pH 7.5). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

	Immobilized Cynomolgus PRLR, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Anti-PRLR Antibody, hFc Tag with the EC50 of 34.6ng/ml determined by ELISA.
	The purity of Cynomolgus PRLR is greater than 95% as determined by SEC-HPLC.
	Cynomolgus PRLR on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.