Name: Human ANGPTL3/Angiopoietin-like 3 Protein (ANG-HM403)
Brand: KactusBio
SKU: ANG-HM403-100UG
Price: 240.0 USD
Availability: InStock

Human ANGPTL3/Angiopoietin-like 3 Protein (ANG-HM403)

Human LILRB2 captured on Protein A chip, can bind Human ANGPTL3, His Tag with an affinity constant of 17.6nM as determined in a SPR assay (Biacore T200).

Immobilized Human ANGPTL3, His Tag at 1 ug/ml (100ul/Well). Dose response curve for Anti-ANGPTL3 Antibody, hFc Tag with the EC50 of 42.3ng/ml determined by ELISA (QC Test).

Human ANGPTL3 on Bis-Tris PAGE under reduced conditions. The purity is greater than 95%.

Express System: HEK293
Product Tag: C-His-Avi
Purity: > 95% as determined by Bis-Tris PAGE
Activity: Immobilized Human ANGPTL3, His Tag at 1 ug/ml (100ul/Well). Dose response curve for Anti-ANGPTL3 Antibody, hFc Tag with the EC50 of 42.3ng/ml determined by ELISA (QC Test). The affinity constant of 17.6nM as determined in SPR assay (Biacore T200). See testing image for detail.
Amino Acid Range: Ser17-Lys219

Catalog #ANG-HM403

Size

100UG

500UG

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Product Description	Recombinant Human ANGPTL3/Angiopoietin-like 3 Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Ser17-Lys219.
Product Background	ANGPTL3 is a secreted glycoprotein that is structurally related to the angiopoietins. Mature human ANGPTL3 contains an N-terminal coiled coil domain and a C‑terminal fibrinogen-like domain. ANGPTL3 is expressed in the liver from early in development through adulthood. Acts in part as a hepatokine that is involved in regulation of lipid and glucose metabolism. Proposed to play a role in the trafficking of energy substrates to either storage or oxidative tissues in response to food intake.
Product Category	Recombinant Protein / Antibody discovery

Protein	ANGPTL3/Angiopoietin-like 3
Synonyms	ANGPTL3; ANGPT5; ANG-5; Angiopoietin-5; FHBL2; ANL3; Angiopoietin-5; Angiopoietin-like Protein 3
Accession	Q9Y5C1
Species	Human
Biotinylated	no
Amino Acid Range	Ser17-Lys219
Molecular Weight	The protein has a predicted MW of 26.6 kDa. Due to glycosylation, the protein migrates to 30-38 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Human ANGPTL3, His Tag at 1 ug/ml (100ul/Well). Dose response curve for Anti-ANGPTL3 Antibody, hFc Tag with the EC50 of 42.3ng/ml determined by ELISA (QC Test). The affinity constant of 17.6nM as determined in SPR assay (Biacore T200). See testing image for detail.
Product Tag	C-His-Avi
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Human LILRB2 captured on Protein A chip, can bind Human ANGPTL3, His Tag with an affinity constant of 17.6nM as determined in a SPR assay (Biacore T200).
	Immobilized Human ANGPTL3, His Tag at 1 ug/ml (100ul/Well). Dose response curve for Anti-ANGPTL3 Antibody, hFc Tag with the EC50 of 42.3ng/ml determined by ELISA (QC Test).
	Human ANGPTL3 on Bis-Tris PAGE under reduced conditions. The purity is greater than 95%.