Name: Human IL-11R alpha Protein (ILR-HM111)
Brand: KactusBio
SKU: ILR-HM111-100UG
Price: 264.0 USD
Availability: InStock

Express System: HEK293
Product Tag: C-His
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: The affinity constant of 1.86 nM as determined in SPR assay (Biacore T200). See testing image for detail.
Amino Acid Range: Ser24-Ala370

Catalog #ILR-HM111

Size

100UG

500UG

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Human IL-11R alpha Protein (ILR-HM111) Summary

Product Description	Recombinant Human IL-11R alpha Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ser24-Ala370.
Product Background	Abstract Interleukin-11 (IL-11) is a pleiotropic cytokine that belongs to gp130 family. IL-11 and its receptor, IL-11Ra, are expressed in human cancers,human cancer cells expressed a functional IL-11Ra subunit, which triggered signal transduction either by exogenous recombinant human IL-11 or by autocrine production of IL-11 in cells cultured under hypoxic conditions.
Product Category	Recombinant Protein / Antibody discovery / Antibody discovery \| Others

Human IL-11R alpha Protein (ILR-HM111) Specifications/Details

Protein	IL-11R alpha
Synonyms	IL-11R subunit alpha; IL-11R-alpha; IL-11RA; IL11RA
Accession	Q14626-1
Species	Human
Biotinylated	no
Amino Acid Range	Ser24-Ala370
Molecular Weight	The protein has a predicted MW of 38.8 kDa. Due to glycosylation, the protein migrates to 50-55 kDa based on Bis-Tris PAGE result.
Activity	The affinity constant of 1.86 nM as determined in SPR assay (Biacore T200). See testing image for detail.
Product Tag	C-His
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1 EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Human IL-11R alpha, His Tag immobilized on CM5 Chip can bind Human IL-11, His Tag with an affinity constant of 1.86 nM as determined in SPR assay (Biacore T200).
	Human IL-11R alpha on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Human IL-11R alpha is greater than 95% as determined by SEC-HPLC.